Supplementation of vitamin E or a botanical extract as antioxidants to improve growth performance and health of growing pigs housed under thermoneutral or heat-stressed conditions  

作　　者：Ysenia V.Silva‑Guillen Consuelo Arellano Jeffrey Wiegert R.Dean Boyd Gabriela E.Martinez Eric van Heugten 

机构地区：[1]Department of Animal Science,North Carolina State University,Raleigh,NC 27695,USA [2]Department of Statistics,North Carolina State University,Raleigh,NC 27695,USA [3]Department of Animal Science,Texas A&M University,College Station,TX 77843,USA [4]Animal Nutrition Research,LLC,Alvaton,KY 42122,USA.

出　　处：《Journal of Animal Science and Biotechnology》2024年第3期1101-1118,共18页畜牧与生物技术杂志（英文版）

基　　金：YVSG was funded by a doctoral scholarship provided by the Peruvian National Fund,for Scientific,Technological,and Technological Innovation Development(FONDECYT);the funding branch of the National Council for Science,Technological,and Technological Innovation Development(CONCYTEC),Peru(grant contract No 233-2015-FONDECYT).

摘　　要：Background Heat stress has severe negative consequences on performance and health of pigs,leading to significant economic losses.The objective of this study was to investigate the effects of supplemental vitamin E and a botanical extract in feed or drinking water on growth performance,intestinal health,and oxidative and immune status in grow-ing pigs housed under heat stress conditions.Methods Duplicate experiments were conducted,each using 64 crossbred pigs with an initial body weight of 50.7±3.8 and 43.9±3.6 kg and age of 13-week and 12-week,respectively.Pigs(n=128)were housed individually and assigned within weight blocks and sex to a 2×4 factorial arrangement consisting of 2 environments(thermo-neutral(21.2℃)or heat-stressed(30.9℃))and 4 supplementation treatments(control diet;control+100 IU/L of D-α-tocopherol in water;control+200 IU/kg of DL-α-tocopheryl-acetate in feed;or control+400 mg/kg of a botanical extract in feed).Results Heat stress for 28 d reduced(P≤0.001)final body weight,average daily gain,and average daily feed intake(-7.4 kg,-26.7%,and-25.4%,respectively)but no effects of supplementation were detected(P>0.05).Serum vitamin E increased(P<0.001)with vitamin E supplementation in water and in feed(1.64 vs.3.59 and 1.64 vs.3.24),but not for the botanical extract(1.64 vs.1.67 mg/kg)and was greater when supplemented in water vs.feed(P=0.002).Liver vitamin E increased(P<0.001)with vitamin E supplementations in water(3.9 vs.31.8)and feed(3.9 vs.18.0),but not with the botanical extract(3.9 vs.4.9 mg/kg).Serum malondialdehyde was reduced with heat stress on d 2,but increased on d 28(interaction,P<0.001),and was greater(P<0.05)for antioxidant supplementation compared to control.Cellular proliferation was reduced(P=0.037)in the jejunum under heat stress,but increased in the ileum when vitamin E was supplemented in feed and water under heat stress(interaction,P=0.04).Tumor necrosis factor-αin jejunum and ileum mucosa decreased by heat stress(P<0.05)and was reduced by vitamin E sup-plementations

关 键 词：Botanical extract Growing pigs Heat stress Immune status Oxidative status TOCOPHEROL Water 

分 类 号：S828.5[农业科学—畜牧学]