Interactions between maternal parity and feed additives drive the composition of pig gut microbiomes in the post‑weaning period  

作　　者：Kayla Law Eduardo Rosa Medina Garcia Chad Hastad Deborah Murray Pedro E.Urriola Andres Gomez 

机构地区：[1]Department of Animal Science,University of Minnesota,1364 Eckles Avenue,Saint Paul,MN 55108,USA [2]New Fashion Pork,164 Industrial Parkway,Jackson,MN 56143,USA

出　　处：《Journal of Animal Science and Biotechnology》2024年第3期1241-1257,共17页畜牧与生物技术杂志（英文版）

基　　金：This study was partially supported by funds from the Agricultural Research,Education,Extension and Technology Transfer(AGREETT)and MNDrive Global Food Ventures Programs,both from the University of Minnesota;Partial funding was supplied by BioZyme,Inc,St.Joseph,Missouri,USA and New Fashion Pork,Jackson,MN,USA.

摘　　要：Background Nursery pigs undergo stressors in the post-weaning period that result in production and welfare chal-lenges.These challenges disproportionately impact the offspring of primiparous sows compared to those of mul-tiparous counterparts.Little is known regarding potential interactions between parity and feed additives in the post-weaning period and their effects on nursery pig microbiomes.Therefore,the objective of this study was to investigate the effects of maternal parity on sow and offspring microbiomes and the influence of sow parity on pig fecal microbi-ome and performance in response to a prebiotic post-weaning.At weaning,piglets were allotted into three treat-ment groups:a standard nursery diet including pharmacological doses of Zn and Cu(Con),a group fed a commercial prebiotic only(Preb)based on an Aspergillus oryzae fermentation extract,and a group fed the same prebiotic plus Zn and Cu(Preb+ZnCu).Results Although there were no differences in vaginal microbiome composition between primiparous and mul-tiparous sows,fecal microbiome composition was different(R^(2)=0.02,P=0.03).The fecal microbiomes of primiparous offspring displayed significantly higher bacterial diversity compared to multiparous offspring at d 0 and d 21 post-weaning(P<0.01),with differences in community composition observed at d 21(R^(2)=0.03,P=0.04).When analyzing the effects of maternal parity within each treatment,only the Preb diet triggered significant microbiome distinc-tions between primiparous and multiparous offspring(d 21:R^(2)=0.13,P=0.01;d 42:R^(2)=0.19,P=0.001).Composi-tional differences in pig fecal microbiomes between treatments were observed only at d 21(R^(2)=0.12,P=0.001).Pigs in the Con group gained significantly more weight throughout the nursery period when compared to those in the Preb+ZnCu group.Conclusions Nursery pig gut microbiome composition was influenced by supplementation with an Aspergillus oryzae fermentation extract,with varying effects on performance when combined with pharmacological levels of Zn

关 键 词：Aspergillus prebiotic Copper Feed additives MATERNAL Nursery pig microbiome PARITY Swine microbiome Trace minerals Zinc 

分 类 号：S828.5[农业科学—畜牧学]