从“虚、毒、痰、瘀”论治中枢神经系统白血病  

On the treatment of central nervous system leukemia from the perspective of 'deficiency,toxin,phlegm and stasis'

作　　者：司天宇 马小淋 朱文伟[1] 周永明[1] SI Tianyu;MA Xiaolin;ZHU Wenwei;ZHOU Yongming(Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院,上海200437

出　　处：《中华中医药杂志》2024年第6期2919-2923,共5页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金项目(No.81973798);国家中医药管理局全国名老中医药专家传承工作室(No.国中医药人教函[2022]75号);第七批全国老中医药专家学术经验继承工作(No.国中医药人教函[2022]76号);上海市“十三五”临床重点专科建设项目(No.shslczdzk05201)。

摘　　要：中枢神经系统白血病常导致白血病复发,且预后较差。文章在中医基础理论的指导下,通过对中枢神经系统白血病的危险因素及病理生理进行总结。“虚”是起病之本,“毒”是致病之因,“痰”和“瘀”则是在本病在发生发展中产生并促进病情进一步加重的病理因素。根据本病本虚表实的特征,并针对“虚、毒、痰、瘀”等病理因素,文章提出“健脾补肾、清解邪毒、涤痰化浊、活血化瘀”治法,同时要依据疾病的阶段化裁选方,为中枢神经系统白血病的中医治疗提供新的思路。Central nervous system leukemia(CNSL) often leads to leukemia recurrence and poor prognosis.This article summarized the risk factors and pathophysiology of CNSL under the guidance of traditional Chinese medicine(TCM) theory.'Deficiency' is the root cause of the disease,'toxins' contribute to its pathogenesis,while 'phlegm' and 'stasis' are pathological factors that exacerbate the condition during its development.Based on the characteristic of root vacuity and tip repletion in this disease,and targeting the pathological factors of 'deficiency,toxins,phlegm and stasis',this article proposed the treatment principles of 'strengthening the spleen and nourishing the kidney,clearing pathogenic toxins,eliminating phlegm and turbidity,and promoting blood circulation and resolving stasis',and need select appropriate treatments based on the stage of the disease.It provides a new approach for TCM treatment of CNSL.

关 键 词：中枢神经系统白血病 病因病机 中医药疗法 临床经验 虚 毒 痰 瘀 

分 类 号：R273[医药卫生—中西医结合]