心脏体外震波治疗对冠心病患者心肌灌注及心电图的影响  

Effect of cardiac shock wave therapy on electrocardiogram and myocardial perfusion in coronary artery disease patients

作　　者：田春梅 郑京京 贾娜[1] 张琳 刘保逸[1] 刘君萌[1] 蓝明[1] 刘兵[1] TIAN Chun-mei;ZHENG Jing-jing;JIA Na;ZHANG Lin;LIU Baoyi;LIU Jun-meng;LAN Ming;LIU Bing(Cardiology Department,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Science,Beijing 100730,China)

机构地区：[1]北京医院心内科、国家老年医学中心、中国医学科学院老年医学研究院,北京100730

出　　处：《中国介入心脏病学杂志》2024年第6期317-323,共7页Chinese Journal of Interventional Cardiology

基　　金：北京医院院内课题项目(BJ-2019-159)。

摘　　要：目的探讨心脏体外震波治疗(CSWT)对冠心病患者负荷心肌灌注扫描及心电图结果的影响。方法纳入2016年12月至2022年8月因冠心病在北京医院住院诊治并行CSWT的患者。CSWT为3个月方案,共9次治疗。收集冠心病患者行CSWT前后的临床基本资料、心肌灌注扫描数据和心电图数据。比较CSWT前后心肌灌注扫描结果和心电图参数的变化。结果共有55例冠心病患者,其中男43例,平均年龄为(67.45±8.96)岁。CSWT前后12导联心电图ST段最大位移均无明显变化,心肌灌注扫描显示左心室整体负荷灌注总分(P=0.031)和整体可逆灌注总分(P=0.024)显著改善,静息左心室整体缺血面积显著缩小(P=0.034),差异均有统计学意义。靶节段负荷灌注评分(P=0.002)、靶节段可逆灌注评分(P=0.002)、靶节段负荷缺血面积(P=0.001)明显改善,差异均有统计学意义。结论CSWT对冠心病难治性心绞痛患者心电图ST段最大位移无影响,有助于改善心肌血流灌注,缩小缺血范围。Objective To explore the effect of cardiac shock wave therapy(CSWT)on ST deviation of electrocardiogram and myocardial perfusion imaging in coronary artery disease(CAD)patients.Methods CAD patients who received CSWT in Cardiology Department of Beijing Hospital from December 2016 to August 2022 were enrolled.Three months of CSWT were conducted with a total of 9 times shock wave treatment.Clinical data,myocardial perfusion imaging data and stress electrocardiogram data were collected.Myocardial perfusion score,electrocardiographic data were compared before and after CSWT.Results A total of 55 patients were finally enrolled.There were 43 male and 12 female patients with an average age of(67.45±8.96)years old.ST deviation on 12 leads of electrocardiogram did not show significant difference before and after CSWT.Myocardial perfusion imaging showed global stress perfusion score(P=0.031)and reverse perfusion score(P=0.024).Global rest ischemia score reduced after CSWT(P=0.034).Target stress perfusion score(P=0.002),target reverse perfusion score(P=0.002),target reverse ischemic area(P=0.001)were improved after CSWT.Conclusions CSWT may not influence ST deviation of electrocardiogram,but may improve myocardial ischemia in CAD patients.

关 键 词：冠心病 心脏体外震波治疗 心肌缺血 心电图 

分 类 号：R541[医药卫生—心血管疾病]