经导管射频消融经皮去肾神经术治疗高血压的长期疗效分析  

Long-term efficacy of catheter-based renal sympathetic denervation for hypertension treatment

作　　者：杜小宇 卢成志[1,2] DU Xiao-yu;LU Cheng-zhi(Department of Cardiology,Tianjin First Center Hospital,Tianjin 300192,China;The First Central Clinical School,Tianjin Medical University,Tianjin 300192,China)

机构地区：[1]天津市第一中心医院心内科,天津300192 [2]天津医科大学第一中心临床学院,天津300192

出　　处：《中国介入心脏病学杂志》2024年第6期324-329,共6页Chinese Journal of Interventional Cardiology

基　　金：国家自然科学基金项目(81970303);天津市医学重点学科(专科)建设项目(TJYXZDXK-054B)。

摘　　要：高血压的发病率及死亡率近年来仍在不断升高,在危害人类心血管健康的同时增加了全球健康负担。经皮去肾神经术(RDN)通过抑制肾交感神经活性从而降低血压,具有广泛应用前景并为高血压治疗带来新的希望,其中经导管射频消融去肾交感神经术(RSD)已开展多项大型临床研究且陆续公布了其长期随访结果,引发了对于RDN长期疗效的全新思考。综上因素本文主要针对RSD的长期疗效及其潜在影响因素进行综述,旨在为RDN的临床应用提供参考。The morbidity and mortality of hypertension have increased in recent years,threatening human cardiovascular health and increasing the global health burden.Renal sympathetic denervation(RDN),which reduces blood pressure by inhibiting renal sympathetic nerve activity,is a promising and novel treatment for hypertension.Among them,catheter-based renal sympathetic denervation has already been studied in several large-scale clinical studies,and the long-term follow-up results have been published,which has triggered a new thinking about the long-term efficacy of RDN.Therefore,this article focuses on the long-term efficacy of RSD and its potential influencing factors,aiming to provide a reference for the clinical application of RDN.

关 键 词：经皮去肾神经术 经导管射频消融 高血压 长期疗效 

分 类 号：R544.1[医药卫生—心血管疾病]