全球细菌真菌耐药状况及应对策略  

Global microbial resistance:current status and response strategies

作　　者：余跃天[1] 吴文娟[2] Yu Yuetian;Wu Wenjuan(Department of Critical Care Medicine,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200001,China;Department of Laboratory Medicine,Shanghai East Hospital,Tongji University School of Medicine,Shanghai 200123,China)

机构地区：[1]上海交通大学医学院附属仁济医院重症医学科,上海200001 [2]同济大学附属东方医院南院医学检验科,上海200123

出　　处：《中华检验医学杂志》2024年第6期592-596,共5页Chinese Journal of Laboratory Medicine

基　　金：国家自然科学基金(81971990,82172326)。

摘　　要：21世纪以来,抗微生物药物耐药已成为全世界最重要的公共卫生威胁之一。2023年5月27日第七十六届世界卫生大会达成首个全球感染预防和控制战略,提出全球抗微生物耐药(AMR)行动计划的方向。本文概览全球微生物耐药现状和WHO抗微生物耐药全球研究议题要点,结合我国细菌耐药性变化趋势和耐药防控困境,探讨医疗机构临床与实验室的应对措施,提出多学科合作促进抗微生物药物合理应用是抗击耐药的必由之路。Antimicrobial resistance has emerged as a critical global public health concern since the 21^(st) century.On May 27,2023,the 76th World Health Assembly endorsed the first global infection prevention and control strategy,proposing the direction of the Global Action Plan for Antimicrobial Resistance(AMR).This article provides an overview of the current global landscape of microbial resistance and the key research topics outlined by WHO in the fight against antimicrobial resistance.Combining with the current trends of bacterial resistance in China and the challenges of drug resistance prevention and control,this paper explores the response measures of medical institutions in clinical and laboratory settings,and advocates for interdisciplinary collaboration to promote the rational application of antimicrobial drugs as the most effective way to combat drug resistance.

关 键 词：细菌 真菌 抗生素耐药 预防控制 协作 

分 类 号：R446.5[医药卫生—诊断学]