腹泻患者粪便分离出厄班纳沙门菌ST512型1例  

Etiological identification of Salmonella Urbana ST512 from a diarrhea patient in China

作　　者：曹健[1] 刘玥[2] 王熙 庄海武 肖建伟[1] 许学斌[2] Cao Jian;Liu Yue;Wang Xi;Zhuang Haiwu;Xiao Jianwei;Xu Xuebin(Department of Microbiological Laboratory,Yangpu District Center for Disease Control and Prevention,Shanghai 200090,China;Division of Pathogen Testing and Analysis,Shanghai Center for Disease Control and Prevention,Shanghai 200336,China)

机构地区：[1]上海市杨浦区疾病预防控制中心微生物检验科,上海200090 [2]上海市疾病预防控制中心病原生物检定所,上海200336

出　　处：《中华检验医学杂志》2024年第6期698-700,共3页Chinese Journal of Laboratory Medicine

基　　金：国家重点研发计划(2017YFC1600100)。

摘　　要：患者男,19岁,2023年9月因连续腹泻3 d就诊上海市杨浦区某社区医院,发病前1天夜晚有烧烤店就餐史,病例符合腹泻病监测定义、采集患者粪便拭子运送公共卫生实验室分离病原为“非A~F群沙门菌”,菌株经参比实验室血清分型、耐药表型、全基因组测序和中国沙门菌区域血清型数据库比对鉴定为厄班纳沙门菌ST512型。患者口服左氧氟沙星3 d后康复。A 19-year-old male patient was admitted to a community hospital in Yangpu District of Shanghai in September 2023 due to diarrhea(4 times per day,watery stool)for 3 consecutive days.The patient had a history of eating out at a barbecue restaurant the night before the onset.The case accorded with diarrhea disease surveillance,and the pathogen was isolated as"non-A-F serogroup Salmonella"by the public health laboratory in the area where the patient′s feces swab was collected.The strain was identified as Salmonella Urbana ST512 by serological typing,antimicrobial resistance phenotype,and whole genome sequencing analysis in the Reference Lab,and then compared with the regional serotype database of Salmonella in China.At last,the patient was cured after taking levofloxacin orally for 3 days.

关 键 词：腹泻 沙门菌属 血清分型 基因组 

分 类 号：R446.5[医药卫生—诊断学]