植物miRNA初级转录本编码肽miPEP研究进展  

Research advances on plant miPEP encoded by primary miRNA

作　　者：田文秀 吴巨勋 伊华林[1] TIAN Wenxiu;WU Juxun;YI Hualin(College of Horticulture and Forestry,National Key Laboratory for Germplasm Innovation&Utilization of Horticultural Crops,Wuhan 430070,China)

机构地区：[1]华中农业大学园艺林学学院,果蔬园艺作物种质创新与利用全国重点实验室,武汉430070

出　　处：《植物生理学报》2024年第5期773-783,共11页Plant Physiology Journal

基　　金：国家现代柑橘产业技术体系(CARS-26);湖北省科技创新项目(2023BEB025);江西省农业关键核心技术攻关项目(JXNK202304-01);国家自然科学基金面上项目(32172524)。

摘　　要：miPEP(microRNA-encoded peptide)是由miRNA初级转录本(pri-miRNA)5′区域编码的微肽,能够与其编码序列小开放阅读框(miORF)相互作用以影响相关基因表达。miPEP外源处理植物能够增强pri-miRNA表达,从而促进相应miRNA积累,抑制miRNA靶基因表达,在植物生长发育和抗逆性中发挥作用。因此,miPEP具有成为对环境友好的高效植物生长调节物质的潜力,以改善农艺性状。本文综述了miPEP的发生过程、外源miPEP的吸收与转运过程,概述了miPEP在植物中已发现的功能及作用机制。miPEP(microRNA-encoded peptide)is a micropeptide encoded by the 5'region of the primary miRNA transcript(pri-miRNA).It specifically interacts with its coding sequence,termed the micropeptide open reading frame(miORF),to regulate the expression of target genes.The external application of miPEP has been demonstrated to enhance the expression of pri-miRNA,contributing to increased accumulation of the corresponding miRNA.This process subsequently inhibits the expression of miRNA target genes,leading to modifications in plant phenotypic traits.miPEP plays a significant role in plant growth,development and resistance to abiotic stress.It has the potential to serve as an environmentally friendly and potent plant growth regulator that improves agronomic traits without relying on genetic approaches.In our review,the generation of miPEP,as well as the absorption and transport of exogenous miPEP were reviewed.Additionally,the functions and mechanisms of miPEP identified in plants were summarized.

关 键 词：miPEP 发生过程 吸收与转运 功能 作用机制 

分 类 号：Q943.2[生物学—植物学]