抗风湿药物胃肠道损伤管理中国专家共识(2024版)  

Chinese expert consensus on the management of anti-rheumatic drug-induced gastrointestinal injury (2024 edition)

作　　者：黄红[1] 段利华 姜林娣 谈文峰[4] 薛静[5] 程永静[6] 李景南[7] 吕宾[8] 吴开春 张卓莉[1] 赵岩[10] 中华医学会风湿病学分会 中国初级卫生保健基金会风湿免疫学专委会 Huang Hong;Duan Lihua;Jiang Lindi;Tan Wenfeng;Xue Jing;Cheng Yongjing;Li Jingnan;Lyu Bin;Wu Kaichun;Zhang Zhuoli;Zhao Yan;behalf of Chinese Rheumatology Association;Committee of Rheumatology and Immunology Subsidiary to Primary Health Care Foundation of China(Department of Rheumatology and Immunology,Peking University First Hospital,Beijing 100034,China;Department of Rheumatology and Immunology,Jiangxi Provincial People′s Hospital,Nanchang 330006,China;Department of Rheumatology and Immunology,Zhongshan Hospital Affiliated to Fudan University,Shanghai 200032,China;Department of Rheumatology and Immunology,Jiangsu Provincial People′s Hospital,Nanjing 210029,China;Department of Rheumatology and Immunology,the Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou 310003,China;Department of Rheumatology and Immunology,Beijing Hospital,Beijing 100005,China;Department of Gastroenterology,Peking Union Medical College Hospital,Beijing 100730,China;Department of Gastroenterology,The First Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310006,China;Department of Gastroenterology,Xijing Hospital,Xi′an 710032,China;Department of Rheumatology and Immunology,Peking Union Medical College Hospital,Beijing 100730,China;不详)

机构地区：[1]北京大学第一医院风湿免疫科,北京100034 [2]江西省人民医院风湿免疫科,南昌330006 [3]复旦大学附属中山医院风湿免疫科,上海200032 [4]江苏省人民医院风湿免疫科,南京210029 [5]浙江大学医学院附属第二医院风湿免疫科,杭州310003 [6]北京医院风湿免疫科,北京100005 [7]北京协和医院消化科,北京100730 [8]浙江中医药大学附属第一医院消化科,杭州310006 [9]西京医院消化科,西安710032 [10]北京协和医院风湿免疫科,北京100730 [11]不详

出　　处：《中华风湿病学杂志》2024年第5期293-302,共10页Chinese Journal of Rheumatology

摘　　要：风湿免疫病患者在接受抗风湿药物治疗过程中可能出现一系列不良反应,其中胃肠道损伤较为常见。由抗风湿药物引起的胃肠道损伤不仅危害患者健康,而且显著增加了医疗费用。为了使临床医生科学、规范地管理抗风湿药物相关的胃肠道损伤,本共识团队通过对常用抗风湿药物相关胃肠道不良事件及防治方法进行文献检索、文献质量评价,基于循证医学证据制定了《抗风湿药物胃肠道损伤管理中国专家共识》。该共识包括总则的3条陈述和细则的12条推荐意见,提出了风湿免疫病对胃肠道的影响及其表现,抗风湿药物引起胃肠道损伤的机制,风湿免疫病患者服用抗风湿药物相关胃肠道损伤的危险因素,以及抗风湿药物相关胃肠道损伤的防治方法,用于指导临床实践。

关 键 词：风湿免疫病 抗风湿药物 胃肠道损伤 干预措施 共识 

分 类 号：R971.1[医药卫生—药品]