Methyl functionalization of trimesic acid in copper-based metal-organic framework for ammonia colorimetric sensing at high relative humidity  

作　　者：Yuxin Wang Zhengxuan Song Yutao Liu Yang Chen Jinping Li Libo Li Jia Yao 

机构地区：[1]College of Chemical Engineering and Technology,Shanxi Key Laboratory of Gas Energy Efficient and Clean Utilization,Taiyuan University of Technology,Taiyuan 030024,China [2]Department of Gastroenterology,Shanxi Bethune Hospital,Shanxi Academy of Medical Sciences,Tongji Shanxi Hospital,Third Hospital of Shanxi Medical University,Taiyuan 030024,China

出　　处：《Chinese Chemical Letters》2024年第6期211-215,共5页中国化学快报（英文版）

基　　金：the financial support from the National Natural Science Foundation of China(Nos.22090062,22278287,22278288);the Shanxi Province 136 Revitalization Medical Project(General Surgery Department);the Shanxi Provincial Guiding Science and Technology Special Project(No.2021XM42);the Basic Research Program of Shanxi Province(No.202103021224341)。

摘　　要：Exhaled ammonia(NH_(3))can be used as a crucial biomarker of kidney and liver diseases.However,the high humidity in the detection conditions remains a challenge for accurate detection by gas sensors.Herein,a copper-based metal-organic framework(CH_(3)-Cu-BTC)with methyl(CH_(3)^(-))functionalization of trimesic acid was synthesized for NH_(3) colorimetric sensing.The CH_(3)-Cu-BTC exhibited a strong response for 5 ppm NH_(3) with high selectivity under high relative humidity(75%RH).Density functional theory(DFT)simulations indicated that the NH_(3) molecules interacted more strongly with CH_(3)-Cu-BTC than H_(2)O molecules did,and the corresponding color switching was attributed to the lone-pair electron in NH_(3) changing the coordination environment of Cu^(2+)ions,leading to an obviously visible color switching response from ruby green to blue.Based on the tailor-made pore chemistry,the precise detection of trace amounts of NH_(3) in exhaled air was realized through functionalized MOF materials.The strategy used in this study not only offers a new pathway for the rapid detection of low concentration NH_(3) under humid conditions,but also shows a method for early respiration diagnosis of kidney and liver diseases.

关 键 词：Metal-organic framework Ammonia sensing Naked-eye color switching High humidity Respiration diagnosis 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置] O657.3[自动化与计算机技术—控制科学与工程] R313[理学—分析化学]