去氨加压素致伴岛叶及皮层病灶的低钠血症性脑病1例  

Hyponatremic encephalopathy with insular and cortical lesions caused by desmopressin:one case report

作　　者：曾阳桥 李晓琴 牟顺 陶涛 ZENG Yangqiao;LI Xiaoqin;MOU Shun;TAO Tao(Department of Neurology,Affiliated Hospital,Southwest Medical University,Sichuan Luzhou 646000,China)

机构地区：[1]西南医科大学附属医院神经内科,四川泸州646000

出　　处：《中国医院药学杂志》2024年第11期1356-1358,共3页Chinese Journal of Hospital Pharmacy

摘　　要：去氨加压素为精氨酸加压素的衍生物,主要用于中枢性尿崩症、夜间遗尿及血友病等。本文报道了1例以可逆胼胝体压部、岛叶及皮层异常信号为影像学表现的去氨加压素所致低钠血症性脑病,以期提高临床医生对该药所致特殊影像学表现的认识,并强调使用该药时按说明书控制饮水量,避免不良反应发生。As a derivative of arginine vasopressin,desmo⁃pressin is mainly indicated for central diabetes insipidus,noc⁃turnal enuresis and hemophilia.This report described one case of hyponatremic encephalopathy due to desmopressin.Reversible abnormal signals were detected by imaging in cor⁃pus callosum,insula and cortex.The objective to enhance the clinician’s understanding of special imaging manifestations caused by desmopressin.Strict control of water intake should be implemented according to package insert for avoiding adverse reactions.

关 键 词：去氨加压素 低钠血症性脑病 不良反应 岛叶 

分 类 号：R969.3[医药卫生—药理学]