良恶性腹水生化检测相关诊断进展  

Progress in relate diagnosis of biochemical detection of benign and malignant ascites

作　　者：陈洋[1] CHEN Yang(Department of Laboratory,Tianjin Hongqiao Hospital,Tianjin 300100,China)

机构地区：[1]天津市红桥医院检验科,天津300100

出　　处：《中国城乡企业卫生》2024年第5期43-45,共3页Chinese Journal of Urban and Rural Enterprise Hygiene

摘　　要：良恶性腹水可发生于多种疾病中,而不同原因导致的良恶性腹水其治疗方法也不尽相同。常规检查、酶学检查、生化检查、肿瘤标志物检查及细胞学检查等都可以用于该病检查,而生化检查是腹水性质诊断中比较常用的方法。在良恶性腹水诊断中,血清生化免疫学指标检测方法应用较广,但特异性、敏感性存在相应局限性。生化学、细胞学、分子生物学、免疫学等相关检查措施可对腹水的性质进行良好区分,为疾病的诊断提供可靠依据。良恶性腹水采用多种生化指标进行诊断,其中包含胆固醇、血清腹水白蛋白浓度、纤维连接蛋白、腺苷脱氨酶、乳酸脱氢酶、癌胚抗原、游离脂肪酸、端粒酶、葡萄糖、pH值检测等。目前已有大量研究证实上述生化指标在良恶性腹水的诊断中至关重要,对良恶性腹水生化检测的研究意义重大。本文对良恶性腹水相关生化指标的应用和诊断进展进行综述,以期为腹水性质的诊断提供指导。Benign and malignant ascites can occur in a variety of diseases,and different treatment methods are used for benign and malignant ascites caused by different reasons.Routine examination,enzymatic examination,biochemical examination,tumor marker examination and cytological examination can all be used for the examination of the disease,and biochemical examinations are commonly used for the diagnosis of the nature of ascites.In the diagnosis of benign and malignant ascites,serum biochemical and immunological index detection methods are widely used,but there are corresponding limitations in specificity and sensitivity.Biochemistry,cytology,molecular biology,immunology and other related examination measures are used to distinguish the nature of ascites well and provide a reliable basis for the diagnosis of the disease.Multiple biochemical indicators are used for the diagnosis of benign and malignant asctites,including cholesterol,serum ascites albumin concentration,fibronectin,adenosine deaminase,lactate dehydrogenase,carcinoembryonic antigen,free fatty acids,telomerase,glucose and pH value detection,etc.At present,a large number of studies have confirmed that the above-mentioned biochemical indicators are very important in the diagnosis of benign and malignant ascites,and they are of great significance to the study of biochemical detection of benign and malignant ascites.This paper reviews the progress of the application and diagnosis of biochemical indexes in benign and malignant ascites,in order to provide guidance for the diagnosis of the nature of asctites.

关 键 词：良恶性 腹水 生化检验 诊断 

分 类 号：R442.5[医药卫生—诊断学]