南宁市流动人口预防艾滋病母婴传播服务情况及效果  

Service utilization and effectiveness of preventing mother-to-child transmission of HIV among the floating population in Nanning City

作　　者：李江恒 蒋武[1] 毛良勤[1] 唐婉婷 彭远军 言京礼[1] LI Jiangheng;JIANG Wu;MAO Liangqin;TANG Wanting;PENG Yuanjun;YAN Jingli(Nanning Maternal and Child Health Hospital,Nanning 530000,Guangxi,China)

机构地区：[1]南宁市妇幼保健院,南宁530000

出　　处：《中国艾滋病性病》2024年第4期387-391,共5页Chinese Journal of Aids & STD

基　　金：广西卫生健康委员会自筹经费科研课题(Z20211420)。

摘　　要：目的 探讨南宁市流动人口中HIV感染产妇预防母婴传播服务及效果。方法 根据户籍将2010-2021年南宁市上报的1 276例HIV感染产妇分为流动人口组和非流动人口组,收集她们及所生儿童的个案卡数据,采用χ^(2)检验和Logistic回归模型对其特征分布、服务情况和效果以及影响因素进行分析。结果2010-2021年南宁市流动人口HIV感染产妇647例,占50.71%。流动人口组HIV感染产妇所生儿童(简称“艾滋病暴露儿童”)感染率、死亡率及母婴传播率分别为1.43%、2.78%、2.48%。多因素分析结果显示,与非流动人口HIV感染产妇相比,流动人口HIV感染产妇进行孕早期检查(OR=0.690,95%CI:0.547~0.872)和孕期病毒载量检测(OR=0.604,95%CI:0.417~0.874)的可能性较低;与非流动人口艾滋病暴露儿童相比,流动人口艾滋病暴露儿童接受1次抗体检测(OR=0.669,95%CI:0.508~0.881)、2次及以上抗体检测(OR=0.727,95%CI:0.578~0.914)和6次及以上随访(OR=0.781,95%CI:0.623~0.979)的可能性较低,而出现失访的风险较高(OR=1.601,95%CI:1.095~2.340)。结论 人口流动影响HIV感染产妇孕期检查和儿童随访,需加强流动人口管理工作。Objective To explore the service utilization and effectiveness of preventing mother-to-child transmission(MTCT) for HIV-infected women among the floating population in Nanning City. Methods A total of 1 276 pregnant women with HIV infection were divided into the floating population group and the non-floating population group according to their household registration from 2010 to 2021 in Nanning City. The case data of these populations and their offspring were collected and further analyzed using a chi-square test and logistic regression model to investigate their characteristic distribution, service utilization, and effectiveness of MTCT prevention, as well as their influencing factors.Results From 2010 to 2021, 647 cases of pregnant women with HIV infection were identified among the floating population in Nanning, constituting 50.71% of the total. The infection, mortality, and MTCT rates among children born to HIV-infected mothers(HIV-exposed children) in the floating population were 1.43%, 2.78%, and 2.48%, respectively.Multivariate analysis showed that, compared to HIV-infected women in the non-floating population, HIV-infected women in the floating population were less likely to receive prenatal examinations in the first trimester(OR=0.690, 95%CI: 0.547-0.872) and to perform viral load test during pregnancy(OR=0.604, 95%CI: 0.417-0.874). Moreover, compared to HIVexposed children in the non-floating population, HIV-exposed children in the floating population were less likely to receive one HIV antibody test(OR=0.669, 95%CI: 0.508-0.881), two or more HIV antibody tests(OR=0.727, 95%CI:0.578-0.914), and six or more follow-up visits(OR=0.781, 95%CI: 0.623-0.979), while the risk of being lost to follow-up was higher(OR=1.601, 95%CI: 1.095-2.340). Conclusions Population mobility affects the prenatal examination of HIVinfected women and their children's follow-up visits. Thus, it is necessary to strengthen the management of the floating population with HIV infection.

关 键 词：艾滋病病毒 流动人口 母婴传播 失访 

分 类 号：R512.91[医药卫生—内科学]