2011-2022年四川省性病门诊检测HIV/AIDS患者趋势分析  

Trend analysis of patients with HIV/AIDS detected in sexually transmitted disease clinics in Sichuan Province from 2011 to 2022

作　　者：袁风顺 张灵麟[1] 梁姝[1] 卓玛拉措 何芳 曾亚莉[1] 徐梦娇 刘小锦 胡莹[1] 刘伦皓[1] YUAN Fengshun;ZHANG Linglin;LIANG Shu;ZHUOMA Lacuo;HE Fang;ZENG Yali;XU Mengjiao;LIU Xiaojin;HU Ying;LIU Lunhao(Sichuan Center for Disease Control and Prevention,Chengdu 610041,Sichuan,China)

机构地区：[1]四川省疾病预防控制中心,成都610041

出　　处：《中国艾滋病性病》2024年第4期397-403,共7页Chinese Journal of Aids & STD

摘　　要：目的了解四川省性病门诊HIV抗体检测量及发现HIV/AIDS患者的变化趋势,为进一步优化扩大筛查策略提供参考。方法在中国疾病预防控制信息系统下载HIV/AIDS患者历史卡片及HIV抗体检测数据库,不同特征构成变化的趋势分析采用Cochran-Armitage趋势检验,Joinpoint回归模型用于HIV/AIDS患者报告数量、检测量等的变化趋势分析。结果2011-2022年,四川省性病门诊HIV抗体检测量为206.51万人次,占全省各类来源检测总量的0.90%,历年检测量呈上升趋势,平均年度变化百分比(AAPC)为14.48%(95%CI:12.17%~16.24%)、占全省检测总量的比例呈下降趋势(Z=-365.81,P<0.001);性病门诊总有效检出率(新发现患者数/检测量)为4.95‰,历年呈下降趋势,AAPC为-9.08%(95%CI:-11.22%~-6.83%)。性病门诊共检测发现HIV/AIDS患者10223例,占全省发现患者总数的4.13%,历年占比呈下降趋势(Z=-16.20,P<0.001);性病门诊发现患者的数量呈现上升趋势,AAPC为5.57%(95%CI:3.03%~8.34%);15~29岁年龄段占比最高(31.61%),男性(81.85%)为主,异性性传播(71.55%)是主要传播途径,首次CD4细胞<200个/μL的占23.84%,65.34%的报告地和50.32%的居住地是成都市。构成比变化趋势分析显示大专及以上文化程度(Z=6.94,P<0.001)的患者占比呈上升趋势,15~29岁年龄段(Z=-5.81,P<0.001)、同性性传播(Z=-2.36,P<0.05)的患者占比呈下降趋势;患者数量变化趋势分析显示15~29岁年龄段(AAPC=6.25%,95%CI:3.73%~8.76%)、异性性传播(AAPC=3.72%,95%CI:0.98%~6.30%)、首次CD4细胞≥500个/μL(AAPC=6.12%,95%CI:3.44%~8.68%)的患者数呈上升趋势。结论2011-2022年四川省性病门诊HIV抗体检测量和发现的HIV/AIDS患者数量整体呈上升趋势,发现的患者中青年占比较高,但有效检出率整体呈下降趋势,需各级医疗机构性病门诊不断提高检测对象的精准性,动员诊断患有性病和有高危性行为史的就诊者进行HIV检测,最大限度发现感染者。Objective To analyze the trends of change in the volume of HIV antibody testing and patients with HIV/AIDS detected by sexually transmitted disease(STD)clinics in Sichuan Province,in order to provide a reference for further optimizing and expanding screening strategies.Methods Record cards of patients with HIV/AIDS and HIV antibody testing database were downloaded from the Chinese Disease Prevention and Control Information System.The trend analysis of composition changes for different characteristics was conducted using the Cochran–Armitage trend test,and the Joinpoint regression model was used for the trend analysis of changes such as those in the number of HIV/AIDS patients reported and testing volume.Results From 2011 to 2022,the number of HIV antibody tests performed in STD clinics in Sichuan Province was 2.0651 million,accounting for 0.90%of the total volume from various sources in the province.The testing volume showed an upward trend,with an average annual percent change(AAPC)of 14.48%(95%CI:12.17%-16.24%),whereas its share of the total volume showed a downward trend over the years(Z=-365.81,P<0.001).The total effective detection rate(number of newly reported cases/testing volume)of STD clinics was 4.95‰,showing a downward trend and an AAPC of-9.08%(95%CI:-11.22%-6.83%).A total of 10223 patients with HIV/AIDS were detected in STD clinics,accounting for 4.13%of the total cases detected in the province,and its proportion has been decreasing over the years(Z=-16.20,P<0.001).The number of patients detected in STD clinics showed an upward trend,with an AAPC of 5.57%(95%CI:3.03%-8.34%).Among these patients,the age group of 15-29 years represented the highest proportion(31.61%),with a predominance of male patients(81.85%).Heterosexual transmission was the primary route of transmission,accounting for 71.55%,while patients with an initial CD4 count below 200 cells/μL comprised 23.84%.Additionally,65.34%of the reporting areas and 50.32%of residences were located in Chengdu City.Trend analysis of the composition

关 键 词：性病门诊 检测 艾滋病病毒感染者/艾滋病患者 趋势分析 

分 类 号：R512.91[医药卫生—内科学]