机构地区:[1]中国疾病预防控制中心性病艾滋病预防控制中心/传染病溯源预警与决策全国重点实验室,北京102206 [2]青岛市疾病预防控制中心,山东青岛266033 [3]山东省疾病预防控制中心,济南250014
出 处:《中国艾滋病性病》2024年第5期497-502,共6页Chinese Journal of Aids & STD
基 金:国家科技重大专项(2017ZX10201101-002-006)。
摘 要:目的了解2017-2021年青岛市MSM社会组织HIV检测服务的变化情况。方法通过青岛市MSM社会组织获取2017-2021年登记的HIV检测数据及HIV阳性检出人数。将2017-2019年定义为A阶段,2020-2021年定义为突发公共卫生事件(突发事件)阶段,其中2020年1-4月定义为B阶段,2020年5月至2021年12月定义为C阶段。采用生态学研究方法,建立基于泊松分布的中断时间序列模型分析不同阶段MSM社会组织HIV检测数量、HIV阳性检出率的变化情况。采用非参数检验,按年度比较不同阶段HIV受检者年均检测次数和重复检测间隔时间。结果MSM社会组织HIV检测数量在A阶段变化率为1.011(95%CI:1.005~1.017),即平均每月增长1.1%。B阶段,MSM社会组织每月HIV检测数量较预期水平分别下降了58.5%(IRR=0.415,95%CI:0.258~0.668),63.4%(IRR=0.366,95%CI:0.265~0.505),67.8%(IRR=0.322,95%CI:0.237~0.438)和71.6%(IRR=0.284,95%CI:0.182~0.442)。C阶段的第一个月,MSM社会组织HIV检测数量恢复到其预期水平的75.1%(IRR=0.751,95%CI:0.564~1.001),此后无显著变化趋势(P>0.05)。2017-2021年MSM社会组织HIV阳性检出率为4.65%(587/12624),其中B阶段为13.01%(41/315),较预期水平显著上升(P<0.05)。突发事件阶段的HIV受检者重复检测间隔时间较A阶段上升(W=137277,P<0.001)。结论突发事件阶段青岛市MSM社会组织HIV检测数量下降,HIV阳性检出率出现上升。MSM社会组织在HIV感染者发现工作中发挥着重要作用,未来应继续加强对MSM社会组织参与艾滋病防制工作的支持。Objective To understand the changes in HIV testing services provided by men who have sex with men(MSM)community organizations in Qingdao from 2017 to 2021.Methods HIV testing data and the number of HIV positive cases registered by MSM community organizations in Qingdao from 2017 to 2021 were obtained.Phase A was defined as the period from 2017 to 2019,while the outbreak of a public health emergency(PHE)phase was defined as 2020 to 2021,with Phase B from January to April 2020,and Phase C from May 2020 to December 2021.An ecological research method was employed,and a time-series interrupted model based on the Poisson distribution was established to analyze the changes in the number of HIV tests conducted by MSM community organizations and HIV positivity rates across different phases.Non-parametric tests were used to compare the annual average number of tests and the interval between repeat tests per person across different phases by year.Results The change rate in the number of HIV tests conducted by MSM community organizations in Phase A was 1.011(95%CI:1.005-1.017),indicating an average monthly increase of 1.1%.During phase B,the monthly number of HIV tests performed by MSM community organizations decreased by 58.5%(IRR=0.415,95%CI:0.258-0.668),63.4%(IRR=0.366,95%CI:0.265-0.505),67.8%(IRR=0.322,95%CI:0.237-0.438)and 71.6%(IRR=0.284,95%CI:0.182-0.442)compared to expected levels,respectively.In the first month of phase C,the number of HIV tests recovered to 75.1%(IRR=0.751,95%CI:0.564-1.001)of the expected level,with no significant trend of change thereafter(P>0.05).From 2017 to 2021,the HIV positive detection rate of MSM community organizations was 4.65%(587/12624),with 13.01%(41/315)during phase B,showing a significant increase from the expected level(P<0.05).The interval between repeat HIV tests increased among those tested during the PHE phase compared to phase A(W=137277,P<0.001).Conclusions During the PHE phase,there was a decline in the number of HIV tests conducted by MSM community organizations in Qingdao,
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