曲安奈德注射疗法联合负压吸引治疗对阴茎硬结症预后的影响  

Effects of triamcinolone acetonide injection therapy combined with negative pressure suction therapy on the prognosis of penile cavernous sclerosis syndrome

作　　者：王二庆[1] 杨发武 刘刚 张贤生[2] Wang Erqing;Yang Fawu;Liu Gang;Zhang Xiansheng(Department of Urology,Suixi County Hospital of Anhui Province,Huaibei 235000,Anhui,China;Department of Urology,First Affliated Hospital of Anhui Medical University,HeFei 230022,Anhui,China)

机构地区：[1]濉溪县医院,安徽淮北235100 [2]安徽医科大学第一附属医院,安徽合肥230022

出　　处：《中国男科学杂志》2024年第2期119-123,共5页Chinese Journal of Andrology

摘　　要：目的探讨阴茎硬结症(PD)采用曲安奈德注射疗法联合负压吸引治疗对硬结斑块面积、疼痛及预后的影响。方法选取2018年1月—2023年1月于濉溪县医院收治的60例PD患者的临床资料进行回顾性分析,按照治疗方法的不同将其分为对照组(27例)与研究组(33例)。对照组给予维拉帕米注射疗法,研究组给予曲安奈德注射疗法联合负压吸引治疗。比较两组患者的临床疗效,阴茎弯曲度、长度、体积,斑块面积,疼痛程度,勃起功能,不良反应,复发率。结果研究组患者的治疗总有效率高于对照组,差异有统计学意义(P<0.05);两组患者治疗后的阴茎弯曲度小于本组治疗前,长度、体积大于本组治疗前,研究组患者治疗后的阴茎弯曲度小于对照组,长度、体积大于对照组,差异有统计学意义(P<0.05);两组患者治疗后的斑块面积小于本组治疗前,视觉模拟评分法(VAS)评分低于本组治疗前,研究组患者治疗后的斑块面积小于对照组,VAS评分低于对照组,差异有统计学意义(P<0.05);两组患者治疗后的国际勃起功能指数(IIEF⁃5)评分高于本组治疗前,研究组患者治疗后的IIEF⁃5评分高于对照组,差异有统计学意义(P<0.05)。结论曲安奈德注射疗法联合负压吸引用于治疗PD,能够提高临床疗效,改善阴茎弯曲度、长度、体积,缩小斑块面积,缓解疼痛感,改善勃起功能,避免引起不良反应或疾病复发。Objective To investigate the impact of combining triamcinolone acetonide injections with negative pressure suction therapy on plaque size,pain,and outcomes in patients with penile induration(PD).Methods A retrospective analysis was conducted on the clinical data of 60 PD patients admitted to Suixi County Hospital from January 2018 to January 2023.They were divided into the control group(27 cases)and the study group(33 cases)by different treatment methods.The control group was treated with verapamil injection,and the study group was treated with triamcinolone acetonide injection combined with negative pressure suction therapy.The clinical efficacy,penile curvature,length,volume,plaque area,pain level,erectile function,adverse reactions,and recurrence rate of two groups of patients were compared.Results In comparision with the control group,the total effective rate of treatment in the study group was higher,with a statistically significant difference(P<0.05).After treatment,the penile curvature in both groups was smaller than before treatment,and the length and volume were greater,in comparision with the control group,the penile curvature of the study group was smaller,and the length and volume were greater,with a statistically significant difference(P<0.05).After treatment,the plaque area in both groups were smaller than before treatment,and the visual analogue scale(VAS)score was lower,in comparision with the control group,the plaque area of the study group was smaller,and the VAS score was lower,with a statistically significant difference(P<0.05).The International Erectile Function Index Score⁃5(IIEF⁃5)scores in both groups after treatment were higher than those before treatment,in comparision with the control group,the IIEF⁃5 scores of the study group after treatment were higher,with a statistically significant difference(P<0.05).Conclusion The utilization of triamcinolone acetonide injection therapy in conjunction with negative pressure suction in the treatment of PD has been shown to enhance clinical ef

关 键 词：阴茎硬结 曲安奈德 负压吸引 预后 

分 类 号：R697.17[医药卫生—泌尿科学]