基于中医传承辅助平台分析史哲新教授辨治老年缺铁性贫血组方及用药规律  

An analysis of prescriptions and medication rules of Professor SHI Zhexin in treating elderly iron deficiency anemia based on the Traditional Chinese Medicine Inheritance Support System

作　　者：杜阳帆 郭江水[1] 闫理想 史哲新[1] DU Yangfan

机构地区：[1]天津中医药大学第一附属医院,天津300193

出　　处：《中医临床研究》2024年第16期8-14,共7页Clinical Journal Of Chinese Medicine

摘　　要：目的:基于数据挖掘探讨和总结史哲新教授辨治老年缺铁性贫血的思路及组方用药规律。方法:整理史哲新教授2019年7月-2022年6月于天津中医药大学第一附属医院血液科病房诊治的老年缺铁性贫血的病历及处方,筛选得到中药处方,录入中医传承辅助平台V2.5系统,应用该软件的频数统计、关联规则分析及熵聚类等数据挖掘方法,对录入的中药处方进行用药规律分析。结果:共获得处方149首,涉及中药152味,总体药性以温、平为主,药味以甘为主,药物归经多入脾经、胃经;用药频数居前10位的药物依次为陈皮、茯苓、清半夏、党参片、焦山楂、炒鸡内金、焦六神曲、焦麦芽、甘草片、五味子;用药频数居前5位的药对依次为清半夏-陈皮,清半夏-茯苓,陈皮-茯苓,清半夏-陈皮-茯苓,陈皮-党参片;得出药物核心组合18组,新处方7首。结论:缺铁性贫血老年患者有五脏渐衰、气血懈惰的临床特点,中医治疗时需突出补养,尤其注重脾、胃、心的滋养顾护,以温补中焦、健脾和胃,调养气血、养心安神为基本方法。史哲新教授这一处方用药特点可为中医药治疗老年缺铁性贫血提供参考。Objective:To analyze and summarize the prescriptions and medication rules of Professor SHI Zhexin in treating elderly iron deficiency anemia by data mining.Methods:The prescriptions from July 2019 to June 2022 of Professor SHI Zhexin were collected,which were prescribed in the hematology ward of First Teaching Hospital of Tianjin University of Traditional Chinese Medicine.The prescriptions were selected and input into the Traditional Chinese Medicine Inheritance Support System V2.5,and the selected prescriptions were analyzed by frequency analysis,association rules,complex entropy clustering analysis and other data mining methods.Results:A total of 149 prescriptions were collected,involving 152 kinds of Chinese herbs.Among them,warm and neutral herbs accounted for the majority in terms of medicinal natures.Sweet herbs accounted for a large proportion in terms of medicinal flavors.The herbs mainly entered into the spleen,stomach channels.The top ten herbs in use frequency were Chenpi(Pericarpium Citri Reticulatae),Fuling(Poria),Qingbanxia(Rhizoma Pinelliae),Dangshen(Radix Codonopsis),Jianshanzha(Fructus Crataegi),Chaojineijin(Endothelium Corneum Gigeriae Galli),Jiaoliushenqu(Massa Fermentata),Jiaomaiya(Fructus Hordei Germinatus),Gancao(Radix Glycyrrhizae),Wuweizi(Fructus Schisandrae Chinensis).The top five herbal combinations in use frequency were Qingbanxia-Chenpi,Qingbanxia-Fuling,Chenpi-Fuling,Qingbanxia-Chenpi-Fuling,Chenpi-Dangshen.A total of 18 core Chinese medicine combinations were excavated,and seven new prescriptions were obtained.Conclusion:Due to the special clinical characteristic of elderly iron deficiency anemia,which is weakness of five internal organs and sluggishness of Qi(气)and blood,traditional Chinese medicine need to highlight the nourishment when treating,especially pay attention to the nourishment of the spleen,stomach and heart.Warming the middle energizer,making spleen and stomach strong,recuperating Qi and blood,nourishing the mind are the basic methods.The above characteristics of pre

关 键 词：老年缺铁性贫血 中医辅助传承平台 用药规律 

分 类 号：R556.3[医药卫生—血液循环系统疾病]