个体化肠内营养支持在胃肠术后早期应用的临床研究  

Clinical research of individualized enteral nutrition support in early application after gastrointestinal surgery

作　　者：乔祥社 马陈建 苌喜 卞锐 郭攀华 QIAO Xiangshe;MA Chenjian;CHANG Xi;BIAN Rui;GUO Panhua(Department of General Surgery,Bozhou Hospital of Traditional Chinese Medicine,Anhui,Bozhou 236800,China)

机构地区：[1]安徽省亳州市中医院普通外科,安徽亳州236800

出　　处：《中国医药科学》2024年第11期191-194,共4页China Medicine And Pharmacy

基　　金：安徽省亳州市重点研发计划(自筹经费)项目(bzzc2021058)。

摘　　要：目的探讨个体化肠内营养支持在胃肠术后早期应用的可行性。方法选取2021年12月至2022年11月亳州市中医院普通外科收治的胃肠手术患者100例,采用随机数表法将其分为对照组和试验组,每组各50例。对照组给予术后常规处理,试验组在常规治疗基础上实施个体化肠内营养,持续7 d。术后第7天测量实验室指标,并比较两组胃肠功能的恢复情况。结果试验组术后肛门首次排气时间明显短于对照组[(55.41±19.63)h vs.(81.46±19.39)h],血清前白蛋白水平高于对照组[(241.14±65.73)g/L vs.(217.35±51.63)g/L],转铁蛋白高于对照组[(2.44±0.35)g/L vs.(2.18±0.43)g/L],住院时间较对照组短[(11.36±3.71)d vs.(13.52±3.63)d],住院费用较对照组少[(1.97±0.36)万元vs.(2.19±0.49)万元],差异有统计学意义(P<0.05)。两组血清总蛋白水平[(70.55±18.89)g/L vs.(68.16±20.05)g/L]、血清白蛋白水平[(53.22±17.76)g/L vs.(50.76±18.54)g/L]、淋巴细胞计数[(1.60±0.54)×10^(9)/L vs.(1.56±0.55)×10^(9)/L]以及肛门首次排便时间[(89.67±22.31)h vs.(97.77±21.27)h]比较,差异无统计学意义(P>0.05)。结论根据个体情况在胃肠术后早期实施个体化肠内营养支持是可行的,能够促进胃肠功能的快速恢复,从而改善患者的营养状况。Objective To investigate the feasibility of individualized enteral nutrition support in early application after gastrointestinal surgery.Methods A total of 100 patients with gastrointestinal surgery admitted to the Department of General Surgery of Bozhou Hospital of Traditional Chinese Medicine from December 2021 to November 2022 were selected.The patients were assigned to the the control group and experimental group according to the random number table method,with 50 cases in each group.The control group was treated with conventional treatment after operation.While the experimental group was implemented with individualized enteral nutrition on the basis of conventional treatment,lasting for 7 days.The laboratory indices were detected on the 7th day after operation,and the recovery of gastrointestinal function was compared between the two groups.Results The first anal exhaust time in the experimental group after surgery was significantly shorter than that in the control group([55.41±19.63]h vs.[81.46±19.39]h),the levels of prealbumin were higher than those in the control group([241.14±65.73]g/L vs.[217.35±51.63]g/L),the levels of transferrin were higher than those in the control group([2.44±0.35]g/L vs.[2.18±0.43]g/L),the length of hospital stay was shorter than that in the control group([11.36±3.71]g/L vs.[13.52±3.63]g/L),the hospitalization costs were lower than those in the control group([1.97±0.36]million yuan vs.[2.19±0.49]million yuan),with statistically significant differences(P<0.05).There were no statistically significant differences in serum total protein level([70.55±18.89]g/L vs.[68.16±20.05]g/L),serum albumin level([53.22±17.76]g/L vs.[50.76±18.54]g/L),lymphocyte count([1.60±0.54]×10^(9)/L vs.[1.56±0.55]×10^(9)/L),and the first anal defecation time([89.67±22.31]h vs.[97.77±21.27]h)between the two groups(P>0.05).Conclusion It is feasible to implement individualized enteral nutrition support in the early stage after gastrointestinal surgery according to individual conditions,which c

关 键 词：胃肠手术 个体化 肠内营养 营养状况 

分 类 号：R656[医药卫生—外科学] R459.3[医药卫生—临床医学]