T2DM合并急性肾损伤治疗中胰岛素泵持续皮下注射的应用价值  

Application Value of Continuous Subcutaneous Injection of Insulin Pump in the Treatment of T2DM Complicated with Acute Kidney Injury

作　　者：李小凤 刘颖聪 柯巧红 林春菊 LI Xiaofeng;LIU Yingcong;KE Qiaohong;LIN Chunju(Anxi County Hospital,Anxi 362400,Fujian,China)

机构地区：[1]安溪县医院,福建安溪362400

出　　处：《糖尿病新世界》2024年第8期29-32,共4页Diabetes New World Magazine

摘　　要：目的探究2型糖尿病(Type 2 Diabetes Mellitus,T2DM)合并急性肾损伤患者治疗中应用持续皮下注射胰岛素泵的效果。方法回顾性选取2023年2月-2024年1月安溪县医院就诊的98例T2DM合并急性肾损伤患者的临床资料,根据不同治疗方式分为常规组(多次皮下注射胰岛素治疗)、观察组(持续皮下注射胰岛素泵治疗),各49例。比较两组控糖效果、不良反应发生率、肾功能指标。结果治疗14 d后,观察组血糖水平、肾功能指标较常规组均更低,差异有统计学意义(P均<0.05)。观察组不良反应总发生率(2.04%)低于常规组(14.29%),差异有统计学意义(χ^(2)=4.900,P<0.05)。结论T2DM合并急性肾损伤患者治疗中应用持续皮下注射胰岛素泵,控糖效果更佳的同时,不良反应发生率相对较低,肾功能得到明显改善。Objective To explore the efficacy of continuous subcutaneous insulin pump in the treatment of type 2 dia-betes mellitus(T2DM)patients with acute kidney injury.Methods Clinical data of ninty-eight T2DM patients with acute kidney injury treated in Anxi County Hospital from February 2023 to January 2024 were retrospectively se-lected.According to different treatment methods,they were divided into conventional group(multiple subcutaneous in-sulin injection)and observation group(continuous subcutaneous insulin pump injection),with forty-nine cases in each group.The glucose control effect,incidence of adverse reactions and renal function indexes were compared between the two groups.Results After 14 days of treatment,blood glucose level and renal function indexes in the observation group were lower than those in the conventional group,and the differences were statistically significant(both P<0.05).The total incidence of adverse reactions in observation group(2.04%)was lower than that in conventional group(14.29%),and the difference was statistically significant(χ^(2)=4.900,P<0.05).Conclusion In the treatment of T2DM patients with acute kidney injury,continuous subcutaneous injection of insulin pump has better glucose control effect,while the occurrence of adverse reactions is relatively low,and the kidney function is significantly improved.

关 键 词：2型糖尿病 急性肾损伤 连续性肾脏替代治疗 胰岛素泵 肾功能 

分 类 号：R587.2[医药卫生—内分泌]