两种胰岛素用药方式治疗急诊糖尿病酮症酸中毒的临床疗效研究  

Clinical Effect of Two Kinds of Insulin Administration in the Treatment of Emergency Diabetic Ketoacidosis

作　　者：苏怡婧 张珍 杨怡婷 SU Yijing;ZHANG Zhen;YANG Yiting(Army 73rd Group Hospital,Xiamen 361000,Fujian,China)

机构地区：[1]陆军第七十三集团军医院,福建厦门361000

出　　处：《糖尿病新世界》2024年第8期184-187,共4页Diabetes New World Magazine

摘　　要：目的分析两种胰岛素用药方式对糖尿病酮症酸中毒(Dibetic Ketocidosis,DKA)的临床疗效。方法回顾性选取2022年9月-2023年6月陆军第七十三集团军医院收治的98例DKA患者的临床资料,根据治疗方式不同分为两组,各49例。对照组静脉滴注胰岛素,研究组皮下泵入胰岛素。对比两组临床疗效、症状改善时间、血糖水平、不良反应发生率。结果研究组临床疗效优于对照组,差异有统计学意义(P<0.05)。与对照组比较,研究组各项症状改善时间均更短,差异有统计学意义(P均<0.05)。治疗后,研究组各项血糖水平低于对照组,差异有统计学意义(P均<0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。结论采用皮下泵入胰岛素治疗DKA,能够提高疗效,促进症状改善,降低血糖水平,且不良反应较低。Objective To analyze the clinical effects of two types of insulin administration on diabetic ketoacidosis(DKA).Methods The clinical data of ninety-eight DKA patients admitted to Army 73rd Group Hospital from Septem-ber 2022 to June 2023 were retrospectively selected and divided into two groups with forty-nine cases each according to different treatment methods.Insulin was injected intravenously in the control group and pumped subcutaneously in the study group.The clinical efficacy,symptom improvement time,blood glucose level and the incidence of adverse re-actions were compared between the two groups.Results The clinical efficacy of the study group was better than that of the control group,and the difference was statistically significant(P<0.05).Compared with the control group,the im-provement time of all symptoms in the study group was shorter,and the differences were statistically significant(all P<0.05).After treatment,the blood glucose levels in the study group were lower than those in the control group,and the differences were statistically significant(all P<0.05).There was no significant difference in incidence of adverse reac-tions between the two groups(P>0.05).Conclusion The treatment of DKA with subcutaneous insulin pump can im-prove the curative effect,promote the improvement of symptoms,reduce blood glucose level,and have less adverse re-actions.

关 键 词：静脉滴注 皮下泵入 糖尿病 酮症酸中毒 血糖水平 

分 类 号：R587.2[医药卫生—内分泌]