奥硝唑合剂联合一次性根管填充治疗儿童牙体牙髓病的效果研究  

Effect of Ornidazole Mixture Combined with One-time Root Canal Filling on Endodontic Disease in Children

作　　者：赵玲[1] ZHAO Ling(Department of Stomatology,Suining County Hospital of Traditional Chinese Medicine,Xuzhou,Jiangsu Province,221200 China)

机构地区：[1]睢宁县中医院口腔科,江苏徐州221200

出　　处：《世界复合医学》2024年第3期33-36,41,共5页World Journal of Complex Medicine

摘　　要：目的探究儿童牙体牙髓病患儿采用奥硝唑合剂与一次性根管填充联合治疗的效果。方法方便选取2021年1月—2023年7月睢宁县中医院收治的86例儿童牙体牙髓病患儿作为研究对象,采用随机数表法分为对照组和观察组,各43例。对照组选择一次性根管填充进行治疗;观察组在对照组基础上应用奥硝唑合剂。比较两组治疗效果、咀嚼效能、咬合力、炎性指标、并发症发生率。结果观察组的治疗总有效率(97.67%)高于对照组(86.05%),差异有统计学意义(χ^(2)=3.888,P<0.05)。观察组的咀嚼效能、咬合力也高于对照组,差异有统计学意义(P均<0.05)。观察组的肿瘤坏死因子-α(tumor necrosis factor-α,TNF-a)、白细胞介素-6(interleukin-6,IL-6)水平均低于对照组,差异有统计学意义(P均<0.05)。观察组并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论在治疗儿童牙体牙髓病时,奥硝唑合剂与一次性根管填充联合应用能够提高治疗效果,同时改善咀嚼效能、咬合力,降低炎性反应,安全性高。Objective To explore the effect of ornidazole mixture combined with one-time root canal filling on children with endodontic disease.Methods A total of 86 cases of children with pediatric endodontic disease admitted to Suining County Hospital of Traditional Chinese Medicine from January 2021 to July 2023 were conveniently selected as the study subjects,and they were divided into the control group and the observation group,each with 43 cases,by using the method of random number table.The control group chose one-time root canal filling for treatment;the observation group applied ornidazole combination on the basis of the control group.The two groups were compared in terms of treatment effect,masticatory efficiency,occlusal force,inflammatory indexes,and complications rate.Results The total treatment effectiveness of the observation group(97.67%)was higher than that of the control group(86.05%),and the difference was statistically significant(χ^(2)=3.888,P<0.05).The masticatory efficiency and bite force of the observation group were higher than that of the control group,and the differences were statistically significant(both P<0.05).The levels of tumor necrosis factor-α(TNF-a)and interleukin-6(IL-6)in the observation group were lower than those in the control group,and the differences were statistically significant(both P<0.05).The total complication rate of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion In the treatment of endodontics in children,the application of ornidazole composite and disposable root canal filling in a combined manner can improve the therapeutic effect,as well as improve the masticatory efficacy,occlusal force,and reduce the inflammatory reaction,with a high degree of safety.

关 键 词：儿童牙体牙髓病 一次性根管填充 奥硝唑合剂 治疗效果 并发症 

分 类 号：R541[医药卫生—心血管疾病]