醋酸奥曲肽联合王氏保赤丸治疗急性胰腺炎的效果  

Effect of Octreotide Acetate Combined with Wang's Baochi Pill in the Treatment of Acute Pancreatitis

作　　者：郭少勇[1] GUO Shaoyong(Department of Gastroenterology,Funing County People's Hospital,Funing,Jiangsu Province,224400 China)

机构地区：[1]阜宁县人民医院消化内科,江苏阜宁224400

出　　处：《世界复合医学》2024年第3期113-115,139,共4页World Journal of Complex Medicine

摘　　要：目的探究醋酸奥曲肽联合王氏保赤丸治疗急性胰腺炎的临床效果。方法随机选取2017年1月—2023年11月阜宁县人民医院消化内科治疗的60例急性胰腺炎患者作为研究对象,经抛硬币法分为对照组和观察组,各30例。对照组单用醋酸奥曲肽治疗,观察组在对照组基础上加用王氏保赤丸治疗。比较两组治疗的有效性、不良反应以及炎症状态。结果观察组治疗总有效率为93.33%,高于对照组的73.33%,差异有统计学意义(χ^(2)=4.320,P=0.038)。观察组用药不良反应发生率低于对照组,差异有统计学意义(P<0.05)。观察组治疗后C反应蛋白、外周血白细胞计数、降钙素原水平均低于对照组,差异有统计学意义(P均<0.05)。结论醋酸奥曲肽+王氏保赤丸用于急性胰腺炎的临床效果确切,有助于改善机体炎症状态,用药不良反应少,可确保患者安全用药。Objective To explore the clinical effect of octreotide acetate combined with Wang's Baochi pill in the treatment of acute pancreatitis.Methods Sixty cases of acute pancreatitis patients treated in the Department of Gastroenterology of Funing County People's Hospital from January 2017 to November 2023 were randomly selected as the study subjects,and they were divided into the control group and the observation group by the coin-flip method,each with 30 cases.The control group was treated with octreotide acetate alone,and the observation group was treated with Wang's Baochi pill on the basis of the control group.Treatment effectiveness,adverse reactions and inflammatory status were compared between the two groups of patients.Results The total effective rate of treatment in the observation group was 93.33%,higher than that of 73.33%in the control group,and the difference was statistically significant(χ^(2)=4.320,P=0.038).The incidence rate of adverse drug reactions in the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).The average of C-reactive protein,peripheral blood leukocyte count,and procalcitonin water in the observation group was lower than that of the control group after treatment,and the differences were statistically significant(all P<0.05).Conclusion Octreotide acetate+Wang's Baochi pill has a definite clinical effect in the treatment of acute pancreatitis,which is helpful to improve the inflammatory state of the body,and has fewer adverse reactions,which can ensure the safe use of the drug for patients.

关 键 词：醋酸奥曲肽 王氏保赤丸 急性胰腺炎 治疗效果 不良反应 炎症水平 

分 类 号：R4[医药卫生—临床医学]