腹腔镜联合结肠镜手术治疗结直肠癌的临床效果及安全性研究  

Clinical Effects and Safety of Laparoscopic Combined Colonoscopic Sur⁃gery in the Treatment of Colorectal Cancer

作　　者：王亚 唐健 王浩 WANG Ya;TANG Jian;WANG Hao(Department of General Surgery,Baoying County Hospital of Traditional Chinese Medicine,Baoying,Jiangsu Province,)

机构地区：[1]宝应县中医医院普通外科,江苏宝应225800

出　　处：《中外医疗》2024年第13期31-34,共4页China & Foreign Medical Treatment

摘　　要：目的探讨腹腔镜联合结肠镜手术治疗结直肠癌的效果,以及分析治疗的安全性。方法简单随机选取2019年1月—2023年12月宝应县中医医院收治的70例结直肠癌患者为研究对象,以随机数表法分为两组,各35例。对照组行传统开腹手术,观察组行腹腔镜联合结肠镜手术,比较两组术中及术后相关指标、机体免疫指标变化以及并发症发生情况。结果与对照组比较,观察组手术时间(124.92±10.52)min更短,术中出血量(98.86±8.87)mL更少,差异有统计学意义(t=13.413、18.489,P均<0.05)。与对照组比较,观察组术后排气、排便、引流管留置、下床活动与住院时间均更短,差异有统计学意义(P均<0.05)。术前两组免疫指标水平对比,差异无统计学意义(P>0.05);术后3 d,观察组免疫指标水平高于对照组,差异有统计学意义(P<0.05)。观察组并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论结直肠癌患者联合采用腹腔镜与结肠镜手术治疗,可明显改善围术期相关指标,对患者机体免疫功能的影响较小,且并发症风险较低。Objective To explore the effect of laparoscopic combined colonoscopic surgery in the treatment of colorectal cancer,as well as to analyze the safety of treatment.Methods A total of 70 patients with colorectal cancer treated in Baoying County Hospital of Traditional Chinese Medicine from January 2019 to December 2023 were simple randomly selected as the study objects and divided into two groups with 35 cases each by random number table method.The control group underwent traditional open surgery,and the observation group underwent laparoscopic combined colonoscopic surgery.The intraoperative and postoperative relevant indexes,immune indexes and complications were compared between the two groups.Results Compared with the control group,the operation time(124.92±10.52)min in the observation group was shorter,and the intraoperative blood loss(98.86±8.87)mL was less,and the differences were statistically significant(t=13.413,18.489,both P<0.05).Compared with the control group,the postoperative gas evacuation,defecation,drain retention,out-of-bed activities and hospitalization time in the observation group were shorter,and the differences were statistically significant(all P<0.05).There was no significant difference in the level of immune indexes between the two groups before surgery(P>0.05).3 d after operation,the level of immune indexes in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).The total complication rate of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion The combined use of laparoscopic and colonoscopic surgical treatment for colorectal cancer patients can significantly improve the perioperative related indexes,with less impact on the immune function of the patient's body and lower risk of complications.

关 键 词：结直肠癌 腹腔镜 结肠镜手术 免疫功能 安全性 

分 类 号：R4[医药卫生—临床医学]