依托咪酯联合丙泊酚用于老年患者无痛胃肠镜检查的麻醉效果分析  

Analysis of the Anesthetic Effect of Etomidate Combined with Propofol for Painless Gastroenteroscopy in Elderly Patients

作　　者：张杰 赵永梅 岳亮 ZHANG Jie;ZHAO Yongmei;YUE Liang(Shandong Institute of Parasitic Disease Control and Prevention(Digestive Disease Hospital of Shandong First Medical University),Jining,Shandong Province,272100 China)

机构地区：[1]山东省寄生虫病防治研究所(山东第一医科大学附属消化病医院),山东济宁272100

出　　处：《中外医疗》2024年第13期105-108,共4页China & Foreign Medical Treatment

摘　　要：目的探究老年患者进行无痛胃肠镜检查时使用丙泊酚和依托咪酯的效果。方法随机选取2022年1月—2023年6月在山东省寄生虫病防治研究所进行无痛胃肠镜检查的100例老年患者为研究对象,按照随机数表法分为对照组(50例,以舒芬太尼和丙泊酚麻醉)和观察组(50例,在对照组基础上加用依托咪酯)。评价两组麻醉有关时间、生命体征和麻醉不良反应。结果观察组麻醉诱导、麻醉苏醒和恢复定向力用时分别是(32.15±5.63)s、(23.61±4.29)min、(27.11±1.48)min,相比于对照组的(41.64±5.77)s、(30.58±4.68)min、(34.64±1.64)min更短,差异有统计学意义(t=8.323、7.763、24.102,P均<0.05)。麻醉5、10 min时,观察组血压和血氧饱和度较对照组更高,差异有统计学意义(P均<0.05);观察组的麻醉不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。结论接受无痛胃肠镜检查的老年患者使用丙泊酚和依托咪酯进行联合麻醉具有更好的麻醉效果,患者的生命体征更稳定,不良反应更少。Objective To investigate the effects of propofol and etomidate in elderly patients undergoing painless gastroenteroscopy.Methods A total of 100 elderly patients who underwent painless gastroenteroscopy in Shandong Institute of Parasitic Disease Control and Prevention from January 2022 to June 2023 were randomly selected as the study objects.Divided into the control group(50 cases,anesthesia with sufentanil and propofol)and the observation group(50 cases,etomidate was added on the basis of the control group)by random number table method.The time,vital signs and adverse effects of anesthesia were evaluated in the two groups.Results The time of anesthesia induction,anesthesia recovery and orientation recovery in the observation group were(32.15±5.63)s,(23.61±4.29)min and(27.11±1.48)min,respectively,which were shorter than those of the control group(41.64±5.77)s,(30.58±4.68)min and(34.64±1.64)min,and the differences were statistically significant(t=8.323,7.763,24.102,all P<0.05).After 5 and 10 min of anesthesia,blood pressure and blood oxygen saturation in the observation group were higher than those in the control group,and the differences were statistically significant(both P<0.05);the total incidence of anesthesia adverse reactions in observation group was lower than that in control group,and the difference was statistically significant(P<0.05).Conclusion The combination of propofol and etomidate has better anesthetic effect,more stable vital signs and less adverse reactions in elderly patients undergoing painless gastroenteroscopy.

关 键 词：老年患者 无痛胃肠镜检查 丙泊酚 依托咪酯 麻醉效果 

分 类 号：R5[医药卫生—内科学]