母亲反复妊娠丢失与子代健康相关性的研究进展  

Research progress on the correlation between maternal recurrent pregnancy loss and offspring health

作　　者：王予 刘铭 Wang Yu;Liu Ming(Department of Obstetrics,Shanghai East Hospital,Tongji University School of Medicine,Shanghai 200123,China)

机构地区：[1]同济大学附属东方医院产科,上海200123

出　　处：《中华围产医学杂志》2024年第6期516-519,共4页Chinese Journal of Perinatal Medicine

基　　金：上海市浦东新区卫生系统重点专科建设项目(PWZzk2022-11)。

摘　　要：既往反复妊娠丢失不仅损害母亲的身心健康,也增加子代发生神经、心血管、呼吸、消化和血液等系统疾病的风险,威胁子代的远期健康。可能机制涉及遗传因素、免疫、氧化应激、子宫低灌注和胎盘因素等。本文就母亲既往反复妊娠丢失与子代各系统健康的相关性及其机制的研究进展进行综述。Prior recurrent pregnancy loss not only impairs the physical and mental health of the mother,but also increases the risk of neurological,cardiovascular,respiratory,digestive,and hematologic diseases in the offspring,posing a threat to their long-term health.The potential mechanisms related to the formation of these damages may include genetic aspects,immunity,oxidative stress,uterine hypoperfusion,and placental factors.This article reviews the latest research progress on the correlation and mechanisms involved between maternal prior recurrent pregnancy loss and the health of their offspring in various organ systems.

关 键 词：妊娠丢失 子代 远期健康 风险因素 机制 

分 类 号：R714.2[医药卫生—妇产科学]