机构地区:[1]上海市浦东医院,复旦大学附属浦东医院,上海201399
出 处:《上海中医药大学学报》2024年第3期40-44,共5页Academic Journal of Shanghai University of Traditional Chinese Medicine
基 金:上海市浦东新区卫健委卫生计生科研项目(PW2021A-53)。
摘 要:目的:探讨热敏灸联合低强度激光治疗肾精不足型绝经后骨质疏松症患者的疗效。方法:纳入肾精不足型绝经后骨质疏松症患者100例,采用随机数字表分为观察组和对照组,每组各50例。两组患者均给予常规护理干预,对照组患者予低强度激光治疗,观察组患者予热敏灸联合低强度激光治疗,两组疗程均为12周。评价两组患者的临床疗效;采用视觉模拟量表(VAS)评价患者的疼痛症状;治疗前后检测所有患者的第2~4腰椎(L2~L4)及左侧股骨颈的骨密度(BMD)水平;比较两组患者的骨钙素(BGP)水平及尿吡啶酚/尿肌酐(U-Pyd/Cr)比值;采用健康调查简表(SF-36)评估所有患者的生活质量。结果:(1)治疗后,观察组患者的临床疗效总有效率为98.00%,对照组为82.00%,观察组的疗效优于对照组(P<0.05);(2)治疗后,两组患者的疼痛VAS评分均明显降低(P<0.05),且观察组患者的评分明显低于对照组(P<0.05);(3)治疗后,两组患者的L2~L4及左侧股骨颈的BMD水平均升高(P<0.05),且观察组患者的BMD水平高于对照组(P<0.05);(4)治疗后,两组患者的BGP水平均升高、U-Pyd/Cr比值均降低(P<0.05),且观察组患者的BGP水平高于对照组、U-Pyd/Cr比值低于对照组(P<0.05);(5)治疗后,两组患者的SF-36各维度评分均升高(P<0.05),且观察组患者的各维度评分均高于对照组(P<0.05)。结论:热敏灸联合低强度激光治疗绝经后骨质疏松症患者具有较好的临床疗效,可缓解患者的疼痛症状,增加BMD水平,改善骨代谢状态,从而提高患者的生活质量,值得在临床上推广应用。Objective:To explore the effect of thermosensitive moxibustion combined with low-level laser in treating patients of postmenopausal osteoporosis with kidney essence deficiency syndrome.Methods:A total of 100 patients of postmenopausal osteoporosis with kidney essence deficiency syndrome were included,and divided into the observation group and control group by random number table,50 cases in each group.The patients in both groups were given routine nursing intervention,the patients in the control group were treated with low-level laser,and the patients in the observation group were treated with thermosensitive moxibustion combined with low-level laser,with a course of 12 weeks.The clinical effects of the two groups were evaluated.The pain symptoms were evaluated by Visual Analogue Scale(VAS).Before and after treatment,the bone mineral density(BMD)level of lumbar vertebra(L2~L4)and left femoral neck of all patients were detected.The bone gla protein(BGP)level and the ratio of urinary pyridinoline(U-Pyd)/creatinine(Cr)were compared between the two groups.The quality of life was evaluated by the MOS item short from health survey(SF-36).Results:①After treatment,the total clinical effective rates of the observation group and the control group were 98.00%and 82.00%respectively,and the effect of the observation group was superior to the control group(P<0.05).②After treatment,the pain VAS scores of the two groups were significantly decreased(P<0.05),and the score of the observation group was obviously lower than that of the control group(P<0.05).③After treatment,the BMD levels of L2~L4 and left femoral neck in the two groups were increased(P<0.05),and the BMD level of the observation group was higher than that of the control group(P<0.05).④After treatment,the BGP level of the two groups was increased,the ratio of U-Pyd/Cr was decreased(P<0.05),and the BGP level of the observation group was higher than that of the control group,the ratio of U-Pyd/Cr was lower than that of the control group(P<0.05).⑤After treatmen
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