基于功能磁共振成像探索特发性耳鸣脑功能网络改变的研究进展  

Research Progress on the Change of Brain Functional Network in Idiopathic Tinnitus Based on Functional Magnetic Resonance Imaging

作　　者：李柏洁 张雪婷 刘慧林[1] 陈鹏[1] 沈琳博 付渊博[1] LI Baijie;ZHANG Xueting;LIU Huilin;CHEN Peng;SHEN Linbo;FU Yuanbo(Department of Neurology,Beijing Hospital of Traditional Chinese Medicine,Beijing 100010,China)

机构地区：[1]首都医科大学附属北京中医医院神经内科,北京100010

出　　处：《中华耳科学杂志》2024年第2期291-294,共4页Chinese Journal of Otology

基　　金：2021年度“扬帆”计划重点医学专业(重点扶持专业)——中西医结合康复项目(ZYLX202140)。

摘　　要：特发性耳鸣因其机制尚不明确,缺乏特效的治疗方法,是耳鼻喉科常见难题之一。近年来,随着功能磁共振技术快速发展,越来越多的研究认为,耳鸣的病理机制不仅涉及听觉系统,更是听觉、默认、执行控制、突显及注意网络等多个重叠大脑网络之间动态交互的结果。我们综述耳鸣相关大脑功能网络的功能磁共振成像研究进展,为进一步探索耳鸣的病理机制夯实基础,以期为临床治疗特发性耳鸣提供新的作用靶点及干预措施。Idiopathic tinnitus is one of the common problems in otorhinolaryngology because of its unclear mechanism and lack of specific therapeutic methods.With the rapid development of fMRI,more and more researches believe that the pathological mechanism of tinnitus is not only involved in the auditory system,but also the result of dynamic interaction among multiple overlapping brain networks,such as hearing,default,executive control,salience and attention networks.This article reviews the fMRI research progress on the brain function network related to tinnitus and lays a solid foundation for further exploration of the pathogenesis of tinnitus,in order to provide a new target for clinical treatment of idiopathic tinnitus and intervention measures.

关 键 词：特发性耳鸣 功能磁共振 大脑功能网络 研究进展 

分 类 号：R445.2[医药卫生—影像医学与核医学] R764.45[医药卫生—诊断学]