中耳细菌感染对内耳损伤的研究进展  

Progress of research on inner ear damage from middle ear bacterial infection

作　　者：楼锦涛 吴帆[1] 司瑜[1] 张志钢[1] LOU Jintao;WU Fan;SI Yu;ZHANG Zhigang(Department of Otolaryngology Head and Neck Surgery,Sun Yat-Sen Memorial Hospital/Institute of Hearing and Speech-Language Science,Sun Yat-sen University,Guangzhou 510120,China)

机构地区：[1]中山大学孙逸仙纪念医院耳鼻咽喉头颈外科,中山大学听力与语言学研究所,广州510120

出　　处：《中华耳科学杂志》2024年第2期331-334,共4页Chinese Journal of Otology

基　　金：国家自然科学基金(82173154);广东省自然科学基金(2022A1515012436,2021A1515010338)。

摘　　要：中耳细菌感染造成内耳微环境改变是中耳炎内耳损伤的主要原因。我们就近年来有关中耳细菌感染对内耳影响的相关文献进行综述,分析总结中耳炎细菌感染的主要类型、听力损失特点、中耳感染进入内耳的途径及内耳免疫微环境的变化及中耳细菌感染损伤内耳的干预措施,为中耳炎细菌感染对内耳损伤的机制和干预研究提供帮助。Changes in the inner ear microenvironment caused by bacterial infection of the middle ear are the main cause for inner ear damage in otitis media.This article reviews the literature of clinical and basic research on the impact of middle ear bacterial infection on the inner ear published in recent years,and summarizes the main types of bacterial infection in otitis media,characteristics of associated hearing loss,the way middle ear infection spreads to the inner ear,and subsequent changes in the inner ear immune microenvironment,as well as interventions for inner ear damage caused by middle ear bacterial infection,to facilitate research on its mechanisms and management.

关 键 词：中耳炎 细菌感染 内耳 感音神经性听力损失 

分 类 号：R764[医药卫生—耳鼻咽喉科]