“血虚风燥证”皮肤疾病生物学基础研究进展  

Progress in Basic Research on the Biology of"Blood Deficiency and Wind Dryness"in Skin Diseases

作　　者：严格 王怡[1] 杜欣冉 缪晓[1,2] 李福伦[1] YAN Ge;WANG Yi;DU Xinran;MIAO Xiao;LI Fulun(Department of Dermatology,Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China;Innovation Research Institute of Traditional Chinese Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院皮肤科,上海200437 [2]上海中医药大学创新中药研究院,上海200437

出　　处：《皮肤科学通报》2024年第3期229-235,共7页Dermatology Bulletin

基　　金：国家中医药管理局2023年中央财政转移支付地方项目;国家中医药管理局中西医结合与少数民族医药司、重大疑难疾病中西医结合诊疗方案的研究(ZY213-2023-580);上海市科学技术委员会(23Y31920300);上海市卫生健康委员会中医药科研创新团队项目(2022CX011)。

摘　　要：血虚风燥证是中医皮肤病学中的一种常见证候类型,涵盖了多种以皮肤干燥、瘙痒、脱屑为主要临床表现的慢性皮肤疾病,本文通过对血虚风燥证的中医理论渊源进行梳理,阐述其发病机理和病理过程,并且结合现代生物学研究,从遗传、皮肤屏障、代谢、免疫等方面探讨了血虚风燥证的生物学基础。此外,本文阐述了当前中医药和西医治疗血虚风燥证的现状,指出了中西医结合治疗的优势与挑战,以期为皮肤疾病的预防和治疗提供新的思路和方法。Blood deficiency and wind dryness syndrome is common in Chinese medicine dermatology,which covers a variety of chronic skin diseases with dry,itchy and desquamative skin as the main clinical manifestations.In this paper,through tracing back the Chinese medicine theories of blood deficiency and wind dryness syndrome,we have elaborated the pathogenesis and pathological process of the syndrome.Combined with the modern biological research,we have explored the biological basis of the syndrome from the aspects of heredity,skin barriers,metabolism and immunisation.In addition,reviewing the current status of Chinese medicine and Western medicine in the treatment of blood deficiency and wind-dryness syndrome,the advantages and challenges of the combination of Chinese and Western medicine were pointed out to provide new ideas and methods for the prevention and treatment of skin diseases.

关 键 词：皮肤疾病 血虚风燥 生物学基础 中医治法治则 

分 类 号：R751[医药卫生—皮肤病学与性病学]