建和复元方药酒对C57BL/6小鼠毛囊生长和雌雄激素影响  

Effects of"Jianhe Fuyuan Formula"Medicinal Liquor on Hair Follicle Growth and Estrogen and Androgen in C57BL/6 mice

作　　者：刘道楠 韩丽 仇兴华 戴兴业 程望远 朱建文 程凯[1] LIU Dao-nan;HAN Li;QIU Xing-hua;DAI Xing-ye;CHENG Wang-yuan;ZHU Jian-wen;CHENG Kai(School of acupuncture and moxibustion and Massage,Beijing University of Traditional Chinese Medicine,Beijing,102488,China;School of Traditional Chinese Medicine,Beijing University of Traditional Chinese Medicine,Beijing,102488,China;Jianhe Fuyuan Biotechnology(Shenzhen)Co.,Ltd.,Shenzhen Guangdong,518040,China)

机构地区：[1]北京中医药大学针灸推拿学院,北京102488 [2]北京中医药大学中医学院,北京102488 [3]建和复元生物科技(深圳)有限公司,广东深圳518040

出　　处：《中华养生保健》2024年第14期1-4,共4页CHINESE HEALTH CARE

摘　　要：目的观察建和复元方药酒脱发再生、固发止脱的相关功效。方法将小鼠随机分成7组,分别为空白组、白酒组、0.9%氯化钠溶液组、药酒低剂量组、药酒高剂量组、米诺地尔组、高剂量药酒加米诺地尔组,除空白组和米诺地尔组都进行灌胃连续给药15 d后观察药物对小鼠的皮肤颜色、毛囊结构、血清雌激素(E2)、睾丸酮(T)的影响。结果建和复元方药酒低剂量更能增强小鼠的毛发生长速度,能够有效地促进小鼠皮肤的变黑,使小鼠毛发从静止期进入生长期,明显增加毛囊数量,增大毛乳头,深入皮肤内部组织中。结论建和复元方药酒具有基本的脱发再生、固发止脱的作用。Objective To observe the related eff ects of Jianhe Fuyuan prescription wine on hair loss and regeneration,hair and anti-hair loss.Methods The mice were randomly divided into 7 groups:blank group,liquor group,normal saline treatment group,low dose of medicinal liquor group,high dose of medicinal liquor group,minoxidil group,high dose of medicinal liquor and minoxidil group.Except for the blank group and minoxidil group,the skin color,hair follicle structure,serum estradiol(E2)and testosterone(T)of mice were observed after 15 days of continuous administration.Results The low dose of Jianhe Fuyuan prescription wine can enhance the hair growth rate of mice,and can eff ectively promote the blackening of the skin of mice,so that the hair of mice can enter the growth period from the stationary phase,signifi cantly increase the number of hair follicles,increase the dermal papilla,and penetrate into the internal tissues of the skin.Conclusion Jianhe Fuyuan prescription wine has the basic eff ect of hair loss regeneration,hair fi xation and anti-hair loss.

关 键 词：生发 药酒 血清睾酮(T) 雌二醇(E2) 

分 类 号：R24[医药卫生—中医临床基础]