体外受精-胚胎移植患者全身麻醉下卵巢穿刺取卵术后恶心呕吐的影响因素  

Influencing factors of postoperative nausea and vomiting in patients undergoing egg retrieval with general anesthesia for in vitro fertilization-embryo transfer

作　　者：刘金莲[1] 黄琴 韩彩凤 王璐瑜 王洋[1] 王明亚 王洁初 Liu Jinlian;Huang Qin;Han Caifeng;Wang Luyu;Wang Yang;Wang Mingya;Wang Jiechu(Center for Reproductive Medicine,Department of Obstetrics and Gynecology,Peking University Third Hospital,Beijing 100191,China;Department of Anesthesiology,Peking University Third Hospital,Beijing 100191,China)

机构地区：[1]北京大学第三医院妇产科生殖医学中心,北京100191 [2]北京大学第三医院麻醉科,北京100191

出　　处：《中华麻醉学杂志》2024年第6期662-665,共4页Chinese Journal of Anesthesiology

基　　金：北京大学第三医院青年孵育基金(BYSYFY2021048)。

摘　　要：目的:筛选体外受精-胚胎移植(IVF-ET)患者全身麻醉下卵巢穿刺取卵术后恶心呕吐(PONV)的影响因素。方法:本研究为病例对照研究。回顾性收集2020年11月至12月本院生殖医学中心全身麻醉下取卵术的IVF-ET患者病历资料,确定发生PONV患者52例(PONV组),选取未发生PONV患者252例作为对照组(C组)。对可疑影响因素进行单因素分析,差异有统计学意义的因素纳入logistic回归分析模型,筛选PONV的影响因素。结果:与C组比较,PONV组患者取卵数、麻醉时间、PONV和/或晕动病史比率差异有统计学意义( P<0.05);多因素logistic回归分析结果显示:取卵数多、麻醉时间长和PONV和/或晕动病史比率高是PONV的独立危险因素。 结论:取卵数多、麻醉时间长和PONV和/或晕动病史比率高是IVF-ET患者全身麻醉下取卵术PONV的独立危险因素。Objective To identify the influencing factors of postoperative nausea and vomiting(PONV)in the patients undergoing egg retrieval with general anesthesia for in vitro fertilization-embryo transfer(IVF-ET).Methods This was a case-control study.Medical records from IVF-ET patients undergoing egg retrieval with general anesthesia in the Center for Reproductive Medicine in our hospital from November to December 2020 were retrospectively collected,52 patients with PONV were identified(group PONV),and 252 patients without PONV were selected as control group(group C).Univariate analysis was performed on the suspicious influencing factors,and the factors with statistically significant differences were included in the logistic regression analysis model to identify the influencing factors of PONV.Results Compared with group C,statistically significant differences were found in the number of eggs,anesthesia time,and the proportion of PONV history and/or motion sickness history in group PONV(P<0.05).The results of multivariate logistic regression analysis showed that a large number of eggs,long anesthesia time,and a high proportion of PONV history and/or motion sickness history were independent risk factors for PONV.Conclusions A large number of eggs,long anesthesia time,and a high proportion of PONV history and/or motion sickness history are independent risk factors for PONV in IVF-ET patients undergoing egg retrieval with general anesthesia.

关 键 词：体外受精 胚胎移植 麻醉 全身 卵子 手术后恶心呕吐 影响因素分析 

分 类 号：R614[医药卫生—麻醉学]