气相色谱法测定聚乙二醇200中乙二醇、二甘醇、三甘醇和四甘醇含量  

Determination of ethylene glycol,diethylene glycol,triethylene glycol and tetraethylene glycol in polyethylene glycol 200 by gas chromatography

作　　者：孔祥祥 李建兵 陈东 孙晨磊 王婷 孙云 臧金秋 宋蕾 梁野 KONG Xiangxiang;LI Jianbing;CHEN Dong;SUN Chenlei;WANG Ting;SUN Yun;ZANG Jinqiu;SONG Lei;LIANG Ye(Qingdao Research Institute of Product Quality,Qingdao Shandong,266101,China)

机构地区：[1]青岛市产品质量检验研究院,山东青岛266101

出　　处：《质量安全与检验检测》2024年第3期6-9,共4页QUALITY SAFETY INSPECTION AND TESTING

摘　　要：建立气相色谱-氢离子火焰测定聚乙二醇200中乙二醇、二甘醇、三甘醇和四甘醇的测定方法。用一级水将聚乙二醇200稀释后直接测定,前处理操作简单。结果显示,乙二醇、二甘醇、三甘醇和四甘醇在测定浓度范围内线性良好,线性相关系数均大于0.99,回收率分别为93.9%~116.9%,平均相对标准偏差(RSD)为0.19%~1.40%。该方法简单、快速、准确,可以满足聚乙二醇200中乙二醇、二甘醇、三甘醇和四甘醇测定的需要。A gas chromatography-hydrogen ion flame method for the determination of ethylene glycol,diethylene glycol,triethylene glycol and tetraethylene glycol in polyethylene glycol 200 was established.Polyethylene glycol 200 was diluted with primary water and measured directly.The pretreatment operation was simple.The linear correlation coefficients of ethylene glycol,diethylene glycol,triethylene glycol and tetraethylene glycol were all greater than 0.99.The recoveries were 93.9%-116.9%,and the mean relative standard deviations(RSD)were 0.19%-1.40%,respectively.The method is simple,rapid and accurate,and can meet the needs of the determination of ethylene glycol,diethylene glycol,triethylene glycol and tetraethylene glycol in PEG 200.

关 键 词：气相色谱-火焰离子检测器 聚乙二醇200 乙二醇 二甘醇 三甘醇 四甘醇 

分 类 号：TQ460.72[医药卫生—药物分析学]