中医药治疗三阴性乳腺癌用药规律分析  

An Analysis of TCM Medication Patterns for Triple-Negative Breast Cancer

作　　者：冯鸣 黄宏 卞卫和[1] 姚昶[1] FENG Ming;HUANG Hong;BIAN Weihe;YAO Chang(Jiangsu Province Hospital of Chinese Medicine,Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing,Jiangsu,China,210029)

机构地区：[1]江苏省中医院,南京中医药大学附属医院,江苏南京210029

出　　处：《河南中医》2024年第6期893-898,共6页Henan Traditional Chinese Medicine

基　　金：江苏省科技计划专项资金(基础研究计划自然科学基金)面上项目(BK20221424)。

摘　　要：目的:基于中医传承辅助平台分析中医药治疗三阴性乳腺癌的用药规律。方法:通过中国知网、维普、万方数据库检索中医药治疗三阴性乳腺癌的临床文献。应用中医传承辅助平台统计药物的性味、归经频次,分析组方规律和聚类情况,挖掘核心药物组合。结果:共纳入106篇文献,涉及143首方剂和231种中药。常用中药包括白术、柴胡、黄芪等,常用类别包括补虚类、活血化瘀类、清热类等。中药四气以温性最多,五味以甘味最多,归经以肝经最多。常用药物组合包括白术-茯苓、白术-黄芪等。结论:中医药治疗三阴性乳腺癌以补虚药为主,活血化瘀类和化痰止咳平喘类为辅。Objective:To analyze the TCM medication patterns for triple-negative breast cancer based on Chinese Medicine Heritage Assistant Platform.Methods:The clinical literature on TCM treatment for triple-negative breast cancer was retrieved from China National Knowledge Infrastructure(CNKI),VIP,and Wanfang databases.The drug properties,meridian tropism,and frequency were statistically counted using Chinese Medicine Heritage Assistant Platform to analyze the formula-formulation patterns and clustering situation,and to mine the core drug combinations.Results:A total of 106 articles were included,involving 143 formulas and 231 kinds of Chinese medicinals.The commonly-used ones included Baizhu(Rhizoma Atractylodis Macrocephalae),Chaihu(Radix Bupleuri),Huangqi(Radix Scutellariae),etc.,and common categories included the ones for tonifying deficiencies,promoting blood circulation and resolving stasis,and clearing heat,etc.The four natures of Chinese medicinals were mostly warm,and the five flavors were mostly sweet.The most common meridian-tropism was to the liver meridian.Common drug combinations included Baizhu(Rhizoma Atractylodis Macrocephalae)-Fuling(Poria)and Baizhu(Rhizoma Atractylodis Macrocephalae)-Huangqi(Radix Scutellariae),etc.Conclusion:The treatment of triple-negative breast cancer mainly depends on tonifying deficiencies,supplemented by promoting blood circulation and resolving stasis,resolving phlegm,relieving cough and stopping asthma.

关 键 词：三阴性乳腺癌 补虚药物 活血化瘀药物 化痰止咳平喘药物 中医传承辅助平台 

分 类 号：R273.379[医药卫生—中西医结合]