经鼻高流量氧疗与持续气道正压通气模式在急性心力衰竭早期拔管后序贯治疗中的效果比较  

Comparison of the Effects of Trans-nasal High-flow Oxygen Therapy and Continuous Positive Airway Pressure Ventilation Modes in Sequential Treatment of Acute Heart Failure after Early Extubation

作　　者：董为技 Dong Weiji(Wenzhou Cangnan Hospital of Traditional Chinese Medicine,Wenzhou 325800,Zhejiang Province,China)

机构地区：[1]温州市苍南县中医院,浙江温州325800

出　　处：《中外医药研究》2024年第13期75-77,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:探讨急性心力衰竭患者在早期拔管后序贯治疗中应用经鼻高流量氧疗(HFNC)和持续气道正压通气(CPAP)治疗模式的效果差异。方法:选择2021年6月—2023年6月温州市苍南县中医院重症医学科收治的急性心力衰竭且接受机械通气治疗的患者80例作为研究对象,随机分为试验组与常规组,各40例。两组均接受常规治疗,常规组在常规治疗基础上接受CPAP治疗,试验组在常规治疗基础上接受HFNC治疗。比较两组治疗前后美国纽约心脏病协会(NYHA)心功能分级、脑钠肽(BNP)、急性生理与慢性健康评分系统Ⅱ(APACHEⅡ)评分以及血气指标。结果:治疗后,两组NYHA心功能分级优于治疗前,试验组优于常规组,差异有统计学意义(P<0.05);两组BNP水平、APACHEⅡ评分优于治疗前,试验组优于常规组,差异有统计学意义(P<0.05);试验组pH优于治疗前,两组动脉血二氧化碳分压(PaCO_(2))、动脉血氧分压(PaO_(2))优于治疗前,试验组pH值、PaCO_(2)、PaO_(2)优于常规组,差异有统计学意义(P<0.05)。结论:急性心力衰竭患者在早期拔管后序贯治疗中应用HFNC的效果优于CPAP,可明显提高患者心功能及脑钠肽水平,缓解病情,改善血气指标。Objective:To investigate the difference in the effect of the application of trans-nasal high-flow oxygen therapy(HFNC)and continuous positive airway pressure ventilation(CPAP)treatment modes in the sequential treatment of acute heart failure patients after early extubation.Methods:Eighty patients with acute heart failure and receiving mechanical ventilation treatment admitted to the Department of Intensive Care Medicine of Wenzhou Cangnan Hospital of Traditional Chinese Medicine from June 2021 to June 2023 were selected as the study subjects,and were randomly divided into the experimental group and the conventional group,with forty cases in each group.Both groups received conventional treatment,the conventional group received CPAP treatment on the basis of conventional treatment,and the experimental group received HFNC treatment on the basis of conventional treatment.The American New York Heart Association(NYHA)cardiac function classification,brain natriuretic peptide(BNP),Acute Physiology and Chronic Health Scoring SystemⅡ(APACHEⅡ)scores and blood gas indexes were compared between the two groups before and after treatment.Results:After treatment,NYHA cardiac function grading was better than before treatment in both groups,and the experimental group was better than the conventional group,and the difference was statistically significant(P<0.05);BNP levels and APACHEⅡscores were better than before treatment in both groups,and the experimental group was better than the conventional group,and the difference was statistically significant(P<0.05);the pH value of the experimental group was better than that before treatment,and the partial pressure of arterial blood carbon dioxide(PaCO_(2))and partial pressure of arterial blood oxygen(PaO_(2))of the two groups were better than that before treatment,and the experimental group was better than the conventional group in terms of pH,PaCO_(2),and PaO_(2),and the difference was statistically significant(P<0.05).Conclusion:The application of HFNC in early post-extubation s

关 键 词：急性心力衰竭 早期拔管 持续气道正压通气模式 经鼻高流量氧疗 

分 类 号：R541.6[医药卫生—心血管疾病]