5-羟色胺和去甲肾上腺素再摄取抑制剂类药物在神经病理性疼痛中的临床应用进展  

Progress in the Clinical Application of Serotonin and Norepinephrine Reuptake Inhibitors in Neuropathic Pain

作　　者：张莹莹[1] 赵力波[1] 贾霜[1] 李玲梅 Zhang Yingying;Zhao Libo;Jia Shuang;Li Lingmei(Department of Pharmacy,the First Affiliated Hospital of Shandong First Medical University(Qianfoshan Hospital,Shandong Province),Jinan 250000,Shandong Province,China;Medical Management Service Department of Jinan Health Care Development Center,Jinan 250000,Shandong Province,China)

机构地区：[1]山东第一医科大学第一附属医院(山东省千佛山医院)药学部,山东济南250000 [2]济南市康养事业发展中心医疗管理服务部,山东济南250000

出　　处：《中外医药研究》2024年第13期162-164,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：5-羟色胺和去甲肾上腺素再摄取抑制剂(SNRIs)为临床治疗神经病理性疼痛的研究热点。该文围绕SNRIs的临床应用进展作一综述,分析SNRIs的作用机制,总结SNRIs的治疗效果,讨论SNRIs在治疗中的应用挑战与限制,展望SNRIs未来研究方向与应用前景,旨在为SNRIs类药物治疗神经病理性疼痛的研究提供参考。Serotonin and norepinephrine reuptake inhibitors(SNRIs)are a hot topic in the clinical treatment of neuropathic pain.This article reviews the progress of clinical application of SNRIs,analyzes the mechanism of action of SNRIs,summarizes the therapeutic effects of SNRIs,discusses the challenges and limitations of SNRIs in treatment,and looks forward to the future research direction and application prospects of SNRIs,aiming to provide a reference for the study of SNRIs in the treatment of neuropathic pain.

关 键 词：5-羟色胺和去甲肾上腺素再摄取抑制剂 神经病理性疼痛 临床应用 作用机制 

分 类 号：R969[医药卫生—药理学]