参麦注射液治疗气阴两虚型冠心病心绞痛患者的效果观察  

Effect of Shenmai Injection on Patients with Angina Pectoris of Coronary Heart Disease with Qi-Yin Deficiency

作　　者：赖小桃 蒋小莉 焦爱军[1] Lai Xiaotao;Jiang Xiaoli;Jiao Aijun(School of Pharmacy,Guangxi Medical University,Nanning 530021,Guangxi Zhuang Autonomous Region,China;Guangxi Kangsheng Pharmaceutical Co.,LTD,Nanning 530225,Guangxi Zhuang Autonomous Region,China)

机构地区：[1]广西医科大学药学院,广西壮族自治区南宁530021 [2]广西康晟制药有限责任公司,广西壮族自治区南宁530225

出　　处：《中外医药研究》2024年第15期99-101,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

基　　金：贺州市科学研究与技术开发项目(编号:贺科技2023055)。

摘　　要：目的:探讨参麦注射液治疗气阴两虚型冠心病的效果。方法:选取2020年1月—2023年10月贺州市人民医院收治的气阴两虚型冠心病患者120例作为研究对象,使用随机数字法分为观察组与对照组,各60例。对照组采用常规西药治疗,观察组在对照组基础上采用参麦注射液治疗。比较两组治疗效果、6min步行距离、生活质量、不良反应发生率。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P=0.013)。治疗前,两组6min步行距离比较,差异无统计学意义(P>0.05);治疗后,两组6min步行距离长于治疗前,观察组长于对照组,差异有统计学意义(P<0.05)。治疗前,两组生理功能、社会功能、情感职能与精神健康评分比较,差异无统计学意义(P>0.05);治疗后,两组生理功能、社会功能、情感职能与精神健康评分高于治疗前,观察组高于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率低于对照组,差异有统计学意义(P=0.048)。结论:参麦注射液联合常规治疗在气阴两虚型冠心病患者中的效果显著,可改善患者心功能,提高生活质量,减少不良反应。Objective:To investigate the effect of Shenmai injection in treating coronary heart disease with Qi-Yin deficiency.Methods:A total of one hundred and twenty patients with coronary heart disease with Qi-Yin deficiency treated in Hezhou People's Hospital from January 2020 to October 2023 were selected as the research objects,and were divided into observation group and control group by random number method,with sixty cases in each group.The control group was treated with conventional western medicine,and the observation group was treated with Shenmai injection based on the control group.The therapeutic effect,6 min walking distance,quality of life and incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P=0.013).Before treatment,there was no significant difference in 6 min walking distance between the two groups(P>0.05);after treatment,the 6 min walking distance of the two groups was longer than that before treatment,and the observation group was longer than that of the control group,with statistical significance(P<0.05).Before treatment,there was no significant difference in physiological function,social function,emotional function and mental health scores between the two groups(P>0.05);after treatment,the scores of physiological function,social function,emotional function and mental health of the two groups were higher than before treatment,and the observation group was higher than the control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions in observation group was lower than that in control group,and the difference was statistically significant(P=0.048).Conclusion:Shenmai injection combined with conventional treatment in patients with Qi-Yin deficiency type coronary heart disease has a remarkable effect,can improve the heart function of patients,improve the quality of life,reduce adverse reactions.

关 键 词：参麦注射液 气阴两虚型 冠心病 心功能 

分 类 号：R259[医药卫生—中西医结合]