须癣毛癣菌致Majocchi肉芽肿  

Majocchi granuloma caused by Trichophyton mentagrophytes:a case report

作　　者：孙敏 任虹[1] 胡文龙[1] SUN Min;REN Hong;HU Wenlong(Department of Dermatology,Lianyungang First People’s Hospital,Lianyungang 222002,China)

机构地区：[1]连云港市第一人民医院皮肤科,江苏连云港222002

出　　处：《临床皮肤科杂志》2024年第7期416-418,共3页Journal of Clinical Dermatology

摘　　要：报告1例须癣毛癣菌引起的Majocchi肉芽肿。患者男,35岁。面部反复红斑、鳞屑伴肿痛半年。皮肤科检查:面部多发红色结节、斑块及脓疱,可见环形鳞屑。多次真菌镜检结果均阴性,真菌培养及分子生物学鉴定为须癣毛癣菌。皮损组织病理检查:表皮大致正常,真皮及毛囊周围可见较多中性粒细胞和少量多核巨噬细胞浸润。过碘酸希夫染色(PAS)示真皮内可见孢子。诊断:Majocchi肉芽肿。治疗:予口服伊曲康唑0.2 g,每日2次,治疗1个月后皮损消退。随访1年皮损未复发。A case of Majocchi granuloma caused by Trichophyton mentagrophytes is reported.A 35-year-old male presented with a history of multiple erythematous plaques on his face with scales,swelling and pain for half a year.Physical examination showed multiple erythematous nodules,annular scaly plaques with raised edges,and pustules on the face.Multiple microscopic examinations were negative for fungi,and Trichophyton mentagrophytes were identified by fungal culture and molecular testing.Pathological examination of the lesions showed a normal epidermis and a dense neutrophilic infiltrate mixed with scattered multinucleated giant cells in the dermis.A periodic acid-Schiff(PAS)staining revealed fungal spores.A diagnosis of Majocchi granuloma was made.The patient was treated with oral administration of 0.2 g itraconazole twice a day for 1 month;the skin lesions subsided.No recurrence was observed at the 1-year follow-up.

关 键 词：Majocchi肉芽肿 须癣毛癣菌 

分 类 号：R379.2[医药卫生—病原生物学]