雌激素与皮肤健康:生理作用、衰老影响及治疗进展  

Estrogen and Skin Health:Physiological Roles,Effects of Aging,and Prospects for Treatment

作　　者：杨凤娟(综述)[1] 蒋献(审校)[1,2] YANG Fengjuan;JIANG Xian(Department of Dermatology,West China Hospital,Sichuan University,Chengdu 610041,Sichuan,China;Laboratory of Dermatology,Clinical Institute of Infl ammation and Immunology,Frontiers Science Center for Disease-related Molecular Network,West China Hospital,Sichuan University,Chengdu 610041,Sichuan,China)

机构地区：[1]四川大学华西医院皮肤性病科,四川成都610041 [2]四川大学疾病分子网络前沿科学中心免疫炎症研究院皮肤病学研究室,四川成都610041

出　　处：《中国美容医学》2024年第7期181-184,共4页Chinese Journal of Aesthetic Medicine

基　　金：国家自然科学基金面上项目(编号:82273559);四川大学华西医院院-企合作临床研究创新项目(编号:19HXCX010)。

摘　　要：雌激素对机体各个系统的影响已得到充分证明,然而尚未探索的一个领域是雌激素对皮肤的影响。目前,不断发展的皮肤内分泌学认为皮肤不仅是各种激素的靶器官,而且是一个高度活跃的代谢器官,雌激素似乎以多种方式影响着皮肤及皮肤病的发生发展。本文就雌激素的生成特性及相关受体、雌激素对皮肤的生理作用、更年期与皮肤衰老的关系进行回顾,以期为雌激素对皮肤影响的研究提供参考依据。The effects of estrogen on various systems of the body are well documented;however,one area that has not yet been explored is the effect of estrogen on the skin.The currently evolving field of Dermato-Endocrinology considers the skin not only as a target organ for various hormones but also as a highly active metabolic organ where estrogen appears to infl uence the development of skin and dermatosis in multiple ways.In this article,we review estrogen production properties and related receptors,the physiological effects of estrogen on the skin,menopause and skin aging,providing evidence for the study of the effects of estrogen on the skin.

关 键 词：雌激素 皮肤生理作用 皮肤衰老 更年期 

分 类 号：R339.38[医药卫生—人体生理学]