超临界流体色谱-质谱联用技术及其应用研究进展  

Research Progress on Supercritical Fluid Chromatography-Mass Spectrometry and Its Applications

作　　者：葛运程 尚宇瀚 尹磊 马强[1] GE Yun-cheng;SHANG Yu-han;YIN Lei;MA Qiang(Chinese Academy of Inspection and Quarantine,Beijing 100176,China;School of Chemical Engineering,Ocean and Life Sciences,Dalian University of Technology,Panjin 124221,China)

机构地区：[1]中国检验检疫科学研究院,北京100176 [2]大连理工大学化工海洋与生命学院,辽宁盘锦124221

出　　处：《化学试剂》2024年第7期20-28,共9页Chemical Reagents

基　　金：国家市场监督管理总局科技计划项目(2021MK163)。

摘　　要：超临界流体色谱技术因其快速高效的分离方法和绿色环保的分析方法而闻名。由于现代仪器的发展,人们对超临界流体色谱的兴趣显著提升。通过超临界流体色谱分离与质谱检测相结合,使其短时间内实现高选择性、高灵敏度地分析复杂样品中的痕量化合物。超临界流体色谱-质谱联用技术应用报道数量不断增加,并且其应用领域正在迅速扩大。重点关注了近十年来超临界流体色谱-质谱联用技术在食品科学、环境、药学以及医学领域的相关研究,并分析其未来发展潜力。Supercritical fluid chromatography(SFC)is renowned for its high-speed and efficient separations,as well as its environmentally-friendly analytical methods.The advancement of modern instrumentation has reignited interest in SFC.The combination of separation by supercritical fluid chromatography and detection by mass spectrometry enables the analysis of trace compounds in complex samples with high selectivity and sensitivity in a short period of time.The applications of supercritical fluid chromatography-mass spectrometry(SFC-MS)are on the rise and its employment across various fields is rapidly expanding.The article delved into SFC-MS research over the past decade,with a particular focus on fields such as food science,environmental studies,pharmacology,and medicine,and analyzed its potential for future development.

关 键 词：超临界流体色谱-质谱 技术原理 系统结构 应用进展 分析 

分 类 号：O657.7[理学—分析化学]