藤黄属药用植物活性成分的药理作用及其机制研究新进展  

New Progress in the Pharmacological Effects and Mechanisms of Active Ingredients in Medicinal Plants of Garcinia

作　　者：熊嫣 胡逸灵 熊洁 叶演 徐帧欢 刘露婷 龚俊杰[3] 李杰平 邹全明 曾浩 孙红武 Xiong Yan;Hu Yiling;Xiong Jie;Ye Yan;Xu Zhenhuan;Liu Luting;Gong Junjie;Li Jieping;Zou Quanming;Zeng Hao;Sun Hongwu(School of Medicine,Jiangxi University of Technology,Nanchang 330000,China;School of Pharmacy,Jiangxi University of Traditional Chinese Medicine,Nanchang 330000,China;School of Culture and Media,Jiangxi University of Technology,Nanchang 330000,China;National Engineering Research Center of Immunological Products&Department of Microbiology and Biochemical Pharmacy,College of Pharmacy&Lab.Medicine,Army Medical University,Chongqing 400038,China;Chongqing University Cancer Hospital,Chongqing 400030,China)

机构地区：[1]江西科技学院医学院,江西南昌330000 [2]江西中医药大学药学院,江西南昌330000 [3]江西科技学院文化与传媒学院,江西南昌330000 [4]陆军军医大学药学与检验医学系微生物与生化药学教研暨国家免疫生物制品工程技术研究中心,重庆400038 [5]重庆大学附属肿瘤医院血液科,重庆400030

出　　处：《中国野生植物资源》2024年第6期85-90,共6页Chinese Wild Plant Resources

基　　金：国家重点研发计划(2021YFC2302603);国家自然科学基金(32070924,32000651);2023年度江西省大学生创新创业训练计划项目(202310846005);重庆市自然科学基金面上项目(cstc2019jcyj-msxmX0159,CSTB2022NSCQ-MSX0903);重庆市技术创新与应用发展专项重点项目(CQYC20200309239);重庆市高等教育教学改革研究项目(213477)

摘　　要：近年来,由于藤黄属活性成分具有显著的抗炎、抗菌、抗病毒、抗肿瘤等众多药理作用的独特优点而受到研究者广泛关注。藤黄属植物(Garcinia Linn.)所分泌的干燥胶树脂,其化学成分主要有桥环类环氧杂蒽酮、糖、黄酮、三萜等,其活性成分包括藤黄酸、新藤黄酸、α、β-藤黄素,藤黄宁和别藤黄酸等。本文对其抗炎、抗菌、抗病毒、抗肿瘤等药理活性及其作用机制进行较为系统综述,期望为更好地利用与开发藤黄属药用植物奠定坚实基础。Many effects included anti-inflammatory,antibacterial,antiviral,anti-tumor were focused because of their unique advantages of pharmacological action.The dried resin secreted by Garcinia,was characterized by its chemical constituents,which mainly consist of bridging ring epoxides,sugars,flavonoids,triterpenes,etc.Their active components of garcinia cambogia,neo garcinia cambogia,α,β-garcinia cambogia,garcinia cambogia,garcinia cambogia,garcinia cambogia and allogamic acid were reported.Therefore,the recent progress of pharmacological activities and their action mechanisms were reviewed,to lay a solid foundation for the better utilization and development of medicinal plants of Garcinia.

关 键 词：药用植物 藤黄 有效成分 药理活性 作用机制 

分 类 号：R961.1[医药卫生—药理学]