不同呼吸及配准方式对左侧乳腺癌保乳术后放疗摆位误差的影响  

Effect of different breathing and registration methods on radiotherapy positioning error after breast conserving surgery for left breast cancer

作　　者：苏小慧 吴何苟 杨俊国 黄嵘[3] SU Xiaohui;WU Hegou;YANG Junguo;HUANG Rong(School of Medicine,Shantou University,Shantou,Guangdong 515041,China;Department of Oncology and Radiotherapy,Shenzhen People's Hospital,Shenzhen,Guangdong 518020,China;Department of Radiology,Peking University Shenzhen Hospital,Shenzhen,Guangdong 518036,China)

机构地区：[1]汕头大学医学院,广东汕头515041 [2]深圳市人民医院肿瘤放疗科,广东深圳518020 [3]北京大学深圳医院放射科,广东深圳518036

出　　处：《影像研究与医学应用》2024年第13期26-28,共3页Journal of Imaging Research and Medical Applications

摘　　要：目的:比较不同呼吸方式和配准方式对左侧乳腺癌保乳术后放疗摆位误差的影响。方法:连续纳入2023年1月—2024年1月期间在深圳市人民医院诊治的左侧乳腺癌保乳术后进行放疗的74例患者,根据不同呼吸方式分为FB(D0组)、ABC(D1组)和C-RAD(D2组),分别获取前6次及最后一次离线自动骨性配准和自动灰度配准下X轴、Y轴、Z轴及GX、GY、GZ的摆位误差,分别与D0、D1、D2组配准结果,取数据的绝对值,对比分析自动骨性配准下和自动灰度配准下六维方向上的摆位误差。结果:3组患者自动骨性配准下比较X轴、Y轴、Z轴、GX,差异均有统计学意义(P<0.05),X轴、Y轴、Z轴的两两比较结果显示,D2与D0、D1间的差异均有统计学意义(P<0.05)。GX轴两两比较结果显示,D2与D1间的差异有统计学意义(P<0.05)。3组自动灰度配准下的摆位误差比较,Y轴差异有统计学意义(P<0.05),且Y轴两两比较结果显示,D2与D0、D1间的差异有统计学意义(P<0.05)。结论:在制定乳腺癌保乳术后的放疗计划时,应考虑患者的呼吸以及配准方式,以提高放疗的准确性和疗效。Objective To compare the effects of different breathing methods and registration methods on radiotherapy placement errors after breast-conserving surgery for left breast cancer.Methods A total of 74 patients who received radiotherapy after breastconserving surgery for left breast cancer diagnosed and treated at Shenzhen People's Hospital from January 2023 to January 2024 were consecutively included.They were divided into FB(D0 group),ABC(D1 group)and C-RAD(D2 group)according to different breathing methods.We respectively obtained the X-axis,Y-axis,Z-axis and GX,GY,GZ positioning error under the first six and last offline automatic bone registration and automatic grayscale registration;and registration results of D0 group,D1group and D2 group;taking the absolute value of the data,and comparing and analyzing the placement error in the six-dimensional direction under automatic bony registration and automatic grayscale registration.Results Under automatic bone registration,three groups of patients were compared in terms of X-axis,Y-axis,Z-axis,and GX,and the differences were statistically significant(P<0.05).The pairwise comparison results of X-axis,Y-axis,and Z-axis showed that the differences between D2 and D0,D1 were statistically significant(P<0.05).The pairwise comparison of the GX axis showed a statistically significant difference between D2 and D1(P<0.05).The comparison of positioning errors under three groups of automatic grayscale registration showed a statistically significant difference on the Y-axis(P<0.05),and the pairwise comparison results on the Y-axis showed a statistically significant difference between D2,D0,and D1(P<0.05).Conclusion When formulating a radiotherapy plan after breast-conserving surgery for breast cancer,the patient's breathing pattern and registration method should be considered to improve the accuracy and efficacy of radiotherapy.

关 键 词：左侧乳腺癌 保乳术 摆位误差 配准方式 呼吸方式 

分 类 号：R445[医药卫生—影像医学与核医学]