脑电图连通性指标在麻醉药物研究中的进展  

Progress of electroencephalography connectivity in anaesthetic drugs research

作　　者：杨东升 王甜 梁振虎[2] 李民[1] YANG Dongsheng;WANG Tian;LIANG Zhenhu;LI Min(Department of Anesthesiology,Peking University Third Hospital,Beijing 100191,China)

机构地区：[1]北京大学第三医院麻醉科,100191 [2]燕山大学电气工程学院

出　　处：《临床麻醉学杂志》2024年第7期762-765,共4页Journal of Clinical Anesthesiology

基　　金：科技创新2030——“脑科学与类脑研究”重大项目(“科技创新2023+2021ZD0204300”)。

摘　　要：脑电图(EEG)是一种无创脑部电活动测量方法,通过在头皮处安放电极,描记大脑皮层神经细胞所产生的兴奋性和抑制性突触活动的总和。EEG可揭示不同大脑区域的功能及其复杂的相互作用。利用EEG解析麻醉药物在神经中枢的作用机制、判断麻醉深度已成为当前的研究热点。本文拟对EEG的连通性分析方法及其在麻醉药物研究中的应用进行综述,以期进一步探讨未来可能用于研究麻醉药物作用机制的脑电分析方法。Electroencephalography(EEG)is a noninvasive brain-activity measurement technique that uses electrodes placed on the scalp to record the bioelectrical activity of neurons in the cerebral cortex the sum of excitatory and inhibitory synaptic activity.EEG can reveal the function of different brain regions and the complex intercommunication.In recent years,many studies have focused on the use of EEG to analyze the mechanism of general anesthetics and to measure the depth of anesthesia.The connectivity analysis methods of EEG are introduced and their application on anesthetic drugs are reviewed in order to explore other potential EEG analysis methods of drug action mechanism in the future.

关 键 词：脑电图 连通性 麻醉药物 相干 相位同步 格兰杰因果关系 

分 类 号：R614[医药卫生—麻醉学]