Lactate is a potentially harmful substitute for brain glucose fuel:consequences for metabolic restoration of neurotransmission  

作　　者：Oliver Kann Lennart Soder Babak Khodaie 

机构地区：[1]Institute of Physiology and Pathophysiology,Heidelberg University,Heidelberg,Germany [2]Interdisciplinary Center for Neurosciences(IZN),Heidelberg University,Heidelberg,Germany

出　　处：《Neural Regeneration Research》2025年第5期1403-1404,共2页中国神经再生研究（英文版）

摘　　要：The metabolite lactate (L-lactate) can be generated and released by diverse brain cells,including neurons,astrocytes,and oligodendrocytes (Kann,2023;Rae et al.,2024).Lactate production usually requires the degradation of glucose (D-glucose)-and glycogen in astrocytes-to pyruvate by glycolysis and subsequent conversion of pyruvate to lactate by the enzyme lactate dehydrogenase(Figure 1A;Dienel,2019;Rae et al.,2024).

关 键 词：consequences FIGURE RESTORATION 

分 类 号：R338[医药卫生—人体生理学]