集束化口腔护理管理对降低鼻咽癌调强放疗患者放射性口腔黏膜反应的效果  

Effect of clustered oral care management on reducing radiation-induced oral mucositis response in nasopharyngeal carcinoma patients undergoing intensity modulated radiation therapy

作　　者：余玉娇[1] 邓燕萍[1] 叶明蕊[1] 陈丽烟[1] 陈榕钦[1] 张珠儿 邓凤[1] 柏朋刚[1] YU Yujiao;DENG Yanping;YE Mingrui;CHEN Liyan;CHEN Rongqin;ZHANG Zhuer;DENG Feng;BAI Penggang(Fujian Cancer Hospital,Fuzhou 350014,China)

机构地区：[1]福建省肿瘤医院,福建省福州市350014

出　　处：《护理实践与研究》2024年第7期956-963,共8页Nursing Practice and Research

基　　金：福建省卫生健康委员会科研项目(编号:2021Y2014)。

摘　　要：目的评估集束化口腔管理方案对日间鼻咽癌调强放疗患者放射性口腔黏膜(RTOM)反应的影响。方法选取2021年1—12月医院日间治疗的200例鼻咽癌调强放疗患者为研究对象,按照组间基本特征具有可比性的原则分为观察组与对照组,每组100例,对照组给予常规护理,观察组在此基础上采用集束化口腔管理。对比两组患者口腔黏膜炎、口干及口咽疼痛程度、生活质量和药物使用依从性变化。结果干预后,观察组患者发生口腔黏膜炎严重程度低于对照组,组间比较差异有统计学意义(P<0.05);观察组患者发生口干、口咽疼痛评分低于对照组,组间比较差异有统计学意义(P<0.05)。干预前,观察组和对照组患者在生理功能、生理职能、躯体疼痛、一般健康状况、精力、社会功能、情感职能、精神健康8个维度的评分比较差异无统计学意义(P>0.05)。干预后,观察组患者生理功能、生理职能、一般健康状况、精力、社会功能、情感职能和精神健康7个维度得分均高于对照组,躯体疼痛维度得分低于对照组,差异均具有统计学意义(P<0.05)。干预后,观察组患者口腔用药依从性高于对照组,差异有统计学意义(P<0.05)。结论对鼻咽癌调强放疗患者实施集束化口腔管理方案可有效延缓和降低放射性口腔黏膜反应的发生,同时也能缓解在治疗过程中的口干、口咽疼痛问题,从而提升患者的生活质量和口腔用药依从性。Objective To evaluate the effect of a clustered oral management program on radiotherapy-induced oral mucositis(RTOM)response in daytime nasopharyngeal carcinoma patients undergoing intensity modulated radiation therapy.Methods A total of 200 nasopharyngeal carcinoma patients undergoing intensity-modulated radiation therapy who received daytime therapy in the hospital from January to December 2021 were selected as the research subjects.According to the principle of comparability of basic characteristics between the groups,they were divided into an observation group and a control group,with 100 cases in each group.The control group implemented routine nursing care,while the observation group adopted clustered oral care management on this basis.The differences in oral mucositis,pain levels of dry mouth and oropharynx,quality of life,and medication adherence between the two groups of patients were compared.Results After the intervention,the severity of oral mucositis in the observation group was lower than that in the control group,and the difference between the groups was statistically significant(P<0.05);the scores for dry mouth and oropharyngeal pain in the observation group were lower than those in the control group,and the differences between the groups were statistically significant(P<0.05).Before intervention,there was no statistically significant difference in scores of physiological function,physiological role,body pain,general health,vitality,social function,emotional role,and mental health between the two groups(P>0.05).After the intervention,the scores of the observation group were higher than those of the control group in seven dimensions:physiological function,physiological role,general health status,energy,social function,emotional role,and mental health,the body pain score of the observation group was lower than that of the control group,and the differences were statistically significant(P<0.05).After the intervention,the oral medication compliance of patients in the observation group was higher than

关 键 词：集束化 口腔护理 鼻咽癌 放射性口腔黏膜炎 护理效果 

分 类 号：R473.6[医药卫生—护理学]