老年良性前列腺增生术后尿路感染患者衰弱现状及影响因素  

Frailty status and influencing factors in elderly patients with urinary tract infection after surgery for benign prostatic hyperplasia

作　　者：李云 黄雯珊 温海江 Li Yun;Huang Wenshan;Wen HaiJiang(Departmentof Urinary Surgery,Chengmai County People′s Hospital,Chengmai 571900,Hainan Province,China)

机构地区：[1]澄迈县人民医院泌尿外科,海南澄迈571900

出　　处：《中华老年多器官疾病杂志》2024年第6期455-459,共5页Chinese Journal of Multiple Organ Diseases in the Elderly

基　　金：海南省卫生计生行业科研项目(19A200113)。

摘　　要：目的 探讨老年良性前列腺增生术后尿路感染患者衰弱的发生情况及影响因素。方法 回顾性分析2021年3月至2023年3月于澄迈县人民医院医共体总院行手术治疗并于术后发生尿路感染的150例老年良性前列腺增生患者的临床资料。依据术后住院期间衰弱发生情况将患者分为衰弱组(n=68)与非衰弱组(n=82),比较两组患者术前国际前列腺症状评分(IPSS)、合并疾病等情况。采用SPSS 22.0统计软件进行数据分析。根据数据类型分别采用t检验或χ^(2)检验进行组间比较。采用多因素logistic回归分析老年良性前列腺增生术后尿路感染患者衰弱发生的危险因素。结果 衰弱组患者年龄、病程、术前IPSS及住院时间显著多于非衰弱组;合并慢性疾病、饮酒、月收入<1000元、存在营养不良风险或营养不良患者占比显著高于非衰弱组,差异均有统计学意义(P<0.05)。对年龄、病程、术前IPSS、住院时间进行受试者工作特征(ROC)曲线分析,结果显示其对老年良性前列腺增生术后尿路感染患者衰弱有较好的预测价值,曲线下面积分别为0.861、0.988、0.745及0.873(P<0.05)。多因素logistic回归分析结果显示,年龄≥68岁(OR=3.594,95%CI 1.669~7.739)、病程≥2年(OR=5.459,95%CI 1.985~15.013)、术前IPSS≥21分(OR=2.954,95%CI 1.652~5.282)、合并慢性疾病(OR=4.065,95%CI 1.328~12.443)、饮酒(OR=4.254,95%CI 1.654~10.941)、月收入<1000元(OR=1.612,95%CI 1.065~2.440)、住院时间≥8 d(OR=1.258,95%CI 1.005~1.575)、存在营养不良风险或营养不良(OR=3.288,95%CI 1.302~8.303)为老年良性前列腺增生术后尿路感染患者衰弱发生的危险因素。结论 老年良性前列腺增生术后尿路感染患者具有较高衰弱发生风险,且衰弱的发生受到较多因素的影响,临床治疗此类患者时应注重衰弱高危群体的筛查,以尽早采取相应的干预措施。Objective To explore the incidence of frailty and its influencing factors in the elderly patients with urinary tract infection after surgery for benign prostatic hyperplasia(BPH).Methods A retrospective analysis was made of the clinical data of 150 elderly patients who underwent surgical treatment for benign prostatic hyperplasia and developed urinary tract infection in the People′s General Hospital of Chengmai County from March 2021 to March 2023.According to the incidence of frailty during postoperative hospitalization,the patients were divided into frailty group(n=68)and non-frailty group(n=82).The two groups were compared in preoperative international prostatic symptom score(IPSS)and comorbidities.SPSS statistics 22.0 was used for data analysis.t test orχ^(2) test was used to compare the groups according to the data type.Multivariate logistic regression was used to analyze the risk factors of frailty in the elderly patients with urinary tract infection after BPH surgery.Results Age,disease course,preoperative IPSS and hospital stay in the frailty group were significantly higher than those in the non-frailty group,and the proportions of patients with chronic comorbidities,alcohol consumption,monthly income<1000 yuan,risk of malnutrition or malnutrition were significantly higher than those in the non-frailty group(P<0.05).Receiver operating characteristic(ROC)curve analysis for age,disease course,preoperative IPSS and hospital stay showed a good predictive value for the frailty in the elderly patients with urinary tract infection after BPH surgery,and the area under the curve(AUC)was 0.861,0.988,0.745 and 0.873,respectively(P<0.05).Multivariate logistic regression analysis confirmed that age≥68 years(OR=3.594,95%CI 1.669-7.739),disease course≥2 years(OR=5.459,95%CI 1.985-15.013),preoperative IPSS≥21 points(OR=2.954,95%CI 1.652-5.282),chronic diseases(OR=4.065,95%CI 1.328-12.443),alcohol consumption(OR=4.254,95%CI 1.654-10.941),monthly income<1000 yuan(OR=1.612,95%CI 1.065-2.440),length of hospitalizati

关 键 词：老年人 良性前列腺增生 尿路感染 衰弱 

分 类 号：R592[医药卫生—老年医学]