孢子丝菌病样嗜血分枝杆菌感染1例  

Mycobacterium Haemophilum Infection Presenting with Sporotrichosis-Like Reactions:A Case Report

作　　者：何晓玥 杨和荣[1] 于春水[1] 鲁青莲 HE Xiaoyue;YANG Herong;YU Chunshui;LU Qinglian(Department of Dermatology and Venereology,Suining Central Hospital,Suining 629000,China)

机构地区：[1]遂宁市中心医院皮肤病分院,四川遂宁629000

出　　处：《中国皮肤性病学杂志》2024年第7期799-802,共4页The Chinese Journal of Dermatovenereology

摘　　要：患者女,38岁,左上肢多发结节4个月,加重半个月。皮肤科情况:左侧中指掌指关节处、左侧手背、左上臂、肘部伸侧可触及蚕豆至乒乓球大小结节,呈孢子丝菌病样分布,触之质硬无触痛,手背及手掌处结节周围皮肤红肿,部分中央可见黄褐色结痂。组织菌种鉴定结果提示:嗜血分枝杆菌。诊断:系统性红斑狼疮合并嗜血分枝杆菌感染。治疗:予以乳酸环丙沙星、克拉霉素片、利福平胶囊抗感染,吗替麦考酚酯分散片、醋酸泼尼松、硫酸羟氯喹控制红斑狼疮,治疗1个月后皮损部分较前减退;治疗10个月后皮损大部分消退。患者目前仍在随访中。A 38-year-old female patient was admitted to our department due to multiple nodules on her left upper limb for 4 months,which had worsened in the last two weeks.The patient presented with hard and non-tender nodules on the left upper limb with a sporotrichosis-like distribution,ranging in size from a broad bean to a ping-pong ball.Some of the nodules were swollen and others had escharosis in the centre.Testing for Mycobacterium confirmed the presence of Mycobacterium haemophilum.The patient was diagnosed with systemic lupus erythematosus(SLE)combined with Mycobacterium haemophilum infection.We treated the patient′s infection with ciprofloxacin,clarithromycin and rifampicin,while providing standard treatment for SLE.After one month of treatment,the patient′s condition improved,and almost all skin lesions healed after 10 months.The patient is still under follow-up.

关 键 词：系统性红斑狼疮 嗜血分枝杆菌 孢子丝菌病样 

分 类 号：R54[医药卫生—心血管疾病]