外周血降钙素原和中性粒细胞淋巴细胞比值水平对老年绞窄性腹股沟疝的临床诊断价值  

Clinical diagnostic value of peripheral blood procalcitonin and neutrophil lymphocyte ratio levels in elderly patients with strangulated inguinal hernia

作　　者：王志[1] 张谦[2] 周志涛[3] 克力木·阿不都热依木[1] WANG Zhi;ZHANG Qian;ZHOU Zhitao;Kelimu·Abudureyimu(Department of Minimally Invasive,Hernia and Abdominal Surgery,People’s Hospital of Xinjiang Autonomous Region,Urumqi,Xinjiang Uygur Autonomous Region 830011,China;不详)

机构地区：[1]新疆维吾尔自治区人民医院微创、疝与腹壁外科,乌鲁木齐830011 [2]新疆维吾尔自治区人民医院胃肠外科,乌鲁木齐830011 [3]新疆维吾尔自治区人民医院综合外科,乌鲁木齐830011

出　　处：《临床外科杂志》2024年第6期626-629,共4页Journal of Clinical Surgery

基　　金：新疆维吾尔自治区自然科学基金资助项目(2021D01C186)。

摘　　要：目的 探讨外周血降钙素原(PCT)和中性粒细胞淋巴细胞比值(NLR)水平对老年绞窄性腹股沟疝的临床诊断价值。方法 2019年1月~2022年12月收治的老年急性嵌顿性腹股沟疝病人112例,根据术中探查情况分为绞窄组和非绞窄组。多因素Logistic回归分析老年绞窄性腹股沟疝的危险因素。ROC曲线评估外周血PCT和NLR水平对老年绞窄性腹股沟疝的临床诊断价值。结果 绞窄组和非绞窄组病人NLR分别为4.54±1.67和3.78±1.48,PCT分别为(6.74±2.42)ng/ml和(4.97±2.53)ng/ml,两组比较,差异有统计学意义(P<0.05)。多因素Logistic回归分析表明,术前NLR、PCT水平升高是老年绞窄性腹股沟疝发生的危险因素(P<0.05)。NLR和PCT对老年绞窄性腹股沟疝均有较高的临床诊断价值(AUC>0.7),联合检测NLR和PCT能够提高诊断效能(AUC=0.792)。结论 外周血PCT和NLR水平对老年绞窄性腹股沟疝均具有较高的临床诊断价值,联合检测NLR和PCT能够提高诊断效能。Objective To explore the clinical diagnostic value of peripheral blood procalcitonin(PCT)and neutrophil lymphocyte ratio(NLR)levels in elderly patients with strangulated inguinal hernia.Methods The clinical data of 112 elderly patients with acute incarcerated inguinal hernia from January 2019 to December 2022 were retrospectively analyzed,and were divided into strangulated group and non-strangulated group according to the intraoperative exploration.Multivariate Logistic regression analysis of risk factors of strangulated inguinal hernia in the elderly.Evaluation of PCT and NLR levels in peripheral blood by ROC curve in the clinical diagnosis of strangulated inguinal hernia in the elderly.Results The NLR and PCT in the strangulation group[(4.54±1.67)and(6.74±2.42)ng/ml]were higher than those in the non-strangulation group[(3.78±1.48)and(4.97±2.53)ng/ml](P<0.05).Multivariate Logistic regression analysis showed that preoperative NLR and PCT levels were risk factors for strangulated inguinal hernia in the elderly(P<0.05).Both NLR and PCT have high clinical diagnostic value for strangulated inguinal hernia in the elderly(AUC>0.7),and the combined detection of NLR and PCT can improve the diagnostic efficiency(AUC=0.792).Conclusion PCT and NLR levels in peripheral blood have high clinical diagnostic value for strangulated inguinal hernia in the elderly,and combined detection of NLR and PCT can improve the diagnostic efficiency.

关 键 词：降钙素原 中性粒细胞淋巴细胞比值 老年 绞窄性腹股沟疝 

分 类 号：R656.21[医药卫生—外科学]