基于属性层次模型的刺五加注射液临床使用合理性评价  

Rationality Evaluation on Clinical Application of Acanthopanax Senticosus Injection Based on Attribute Hierarchy Model

作　　者：程国亭 胡海锦 徐登球 张进华 CHENG Guoting;HU Haijin;XU Dengqiu;ZHANG Jinhua(Dept.of Pharmacy,Xuancheng Central Hospital,Anhui Xuancheng 242000,China;Dept.of Pharmacy,Beijing Beiya Orthopaedic Hospital,Beijing 102445,China;Key Laboratory of Tumor Immune Microenvironment Research and Therapy,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,China;Medical School,Nanjing University,Nanjing 210093,China;Dept.of Pharmacy,Fujian Maternal and Child Health Hospital,Fuzhou 350001,China)

机构地区：[1]宣城市中心医院药剂科,安徽宣城242000 [2]北京北亚骨科医院药剂科,北京102445 [3]安徽医科大学第一附属医院肿瘤免疫微环境研究及治疗重点实验室,合肥230022 [4]南京大学医学院,南京210093 [5]福建省妇幼保健院药剂科,福州350001

出　　处：《中国医院用药评价与分析》2024年第6期717-721,共5页Evaluation and Analysis of Drug-use in Hospitals of China

基　　金：中国博士后科学基金面上项目(No.2021M691524)。

摘　　要：目的:建立刺五加注射液药物利用评价标准,综合评价刺五加注射液临床使用合理性。方法:以刺五加注射液的药品说明书为基础,参考相关指南和文献,制定刺五加注射液药物利用评价标准。构建12项合理性指标评价体系的属性层次模型,对2022年1—6月宣城市中心医院使用刺五加注射液的546例出院病例进行用药合理性评价。结果:刺五加注射液不合理应用问题主要为适应证不适宜、禁忌证用药、用法与用量不适宜、联合用药不适宜。病例得分(MRS)≥90分的有9例(占1.65%),80分≤MRS<90分的有435例(占79.67%),MRS<80分的有102例(占18.68%)。结论:该院刺五加注射液临床使用问题突出,需加强管理。属性层次模型科学合理、简单快捷,为综合评价药物使用合理性提供了一种新的思路。OBJECTIVE:To establish the criteria for drug utilization evaluation of acanthopanax senticosus injection and comprehensively evaluate the clinical application rationality of acanthopanax senticosus injection.METHODS:Based on drug instructions of acanthopanax senticosus injection,the criteria for drug utilization evaluation of acanthopanax senticosus injection were established with reference to relevant guidelines and literature.The attribute hierarchy model of 12 rationality index evaluation system was constructed to evaluate and analyze 546 discharged patients with acanthopanax senticosus injection in Xuancheng Central Hospital from Jan.to Jun.2022.RESULTS:The irrational problems of acanthopanax senticosus injection mainly included inappropriate indications,contraindications,improper usage and dosage,and inappropriate drug combination.There were 9 cases(1.65%)with medical record score(MRS)≥90 points,435 cases(79.67%)with 80 points≤MRS<90 points,and 102 cases(18.68%)with MRS<80 points.CONCLUSIONS:The clinical application of acanthopanax senticosus injection in the hospital is prominent,and the management needs to be strengthened.The attribute hierarchy model is scientific,rational,simple and fast,and provides a new way to comprehensively evaluate the application rationality.

关 键 词：刺五加注射液 属性层次模型 评价标准 合理性评价 

分 类 号：R932[医药卫生—生药学] R969.3[医药卫生—药学]