改变诱导药物顺序对全麻诱导期呛咳、体动的影响  

Effect of changing the sequence of induction drugs on choking cough and body movement during the induction period of general anesthesia

作　　者：张兴裕 顾育萌 刘铁成[1] ZHANG Xingyu;GU Yumeng;LIU Tiecheng(Department of Anaesthesia,the Second Hospital of Jilin University,Changchun 130041,China)

机构地区：[1]吉林大学第二医院麻醉科,长春130041

出　　处：《长春中医药大学学报》2024年第7期779-782,共4页Journal of Changchun University of Chinese Medicine

基　　金：吉林省教育厅“十三五”科学技术项目(JJKH20190051KJ)。

摘　　要：目的研究改变诱导顺序对全麻诱导期出现呛咳、躯体颤动的作用。方法对100例择期手术女性患者进行随机分组,分别采用诱导顺序A(咪达唑仑-舒芬太尼-依托咪酯-顺式阿曲库铵)和诱导顺序B(舒芬太尼-顺式阿曲库铵-咪达唑仑-依托咪酯-舒芬太尼)。比较2组血压、心率及血氧饱和度;比较2组不良事件发生情况;比较2组麻醉诱导期的呛咳、躯体颤动发生率以及呛咳、躯体颤动程度。结果诱导顺序B组比A组出现呛咳、体动的次数更少,呛咳发生率分别为18%和56%(P<0.05);体动发生率分别为14%和46%(P<0.05)。结论改变诱导药物顺序可以减少诱导期的呛咳和躯体颤动,建议在临床实践中开展相关策略。Objective To study the effect of changing the sequence of induction drugs on choking cough and somatic tremor during the induction period of general anesthesia.Methods 100 female patients undergoing elective surgery were randomly divided into induction sequence A group(midazolam-sufentanil-etomidate-cisatracurium)and induction sequence B group(sufentanilcisatracurium-midazolam-etomidate-sufentanil).Blood pressure,heart rate,and blood oxygen saturation(SpO2)between two groups were compared.The occurrence of adverse events between two groups was compared.The incidence and degree of choking cough and somatic tremor during anesthesia induction between two groups were compared.Results The sequency of choking cough and body movement in induction sequence B group was less than that in induction sequence A group(P<0.05).And the incidence of choking cough in induction sequence B group and induction sequence A group was 18%and 56%,respectively,and the incidence of body movement was 14%and 46%,respectively(P<0.05).Conclusion Changing the sequence of induction drugs can reduce choking cough and somatic tremor during the induction period of general anesthesia.It is recommended to implement relevant strategies in clinical practice.

关 键 词：诱导顺序 诱导期体动 舒芬太尼 镇痛 依托咪酯 

分 类 号：R614[医药卫生—麻醉学]