吲哚菁绿荧光显影在腹腔镜再次胆道探查术中的应用研究  

Application of indocyanine green fluorescence imaging in laparoscopic biliary re-exploration

作　　者：朱超 刘会春 王勇 庞青 潘洪涛 胡小四 陈石磊 周帅 王志成 金浩 ZHU Chao;LIU Huichun;WANG Yong(Department of Hepatobiliary and Pancreatic Surgery,Anhui Second People's Hospital,Hefei 230011,China)

机构地区：[1]安徽省第二人民医院肝胆胰外科,安徽合肥230011

出　　处：《腹腔镜外科杂志》2024年第5期358-362,共5页Journal of Laparoscopic Surgery

基　　金：安徽省高校自然科学研究项目(2023AH053366);安徽省高校自然科学研究项目(2023AH053384)。

摘　　要：目的:探讨吲哚菁绿荧光显影在腹腔镜再次胆道探查术中的应用价值。方法:回顾分析2020年1月至2022年12月行腹腔镜再次胆道探查术的52例患者的临床资料,其中24例行荧光腹腔镜手术(荧光组),28例行普通腹腔镜手术(常规组),对比两组手术相关指标。结果:两组患者基线资料、术中联合胆肠内引流、术后胆漏发生率、结石残留率差异无统计学意义(P>0.05)。荧光组与常规组手术时间[(119.2±44.0)min vs.(159.0±52.4)min]、寻找肝外胆管时间[(21.0±7.8)min vs.(38.8±12.5)min]、出血量[(97.1±61.3)mL vs.(226.8±210.2)mL]、术后感染率(8.3%vs. 32.1%)、胰腺炎发生率(4.2%vs. 28.6%)、术后拔除引流管时间[(2.7±1.1)d vs.(3.8±1.4)d]、术后住院时间[(6.4±2.3)d vs.(10.3±3.2)d]差异均有统计学意义(P<0.05)。结论:腹腔镜再次胆道探查术中应用吲哚菁绿荧光显影是安全、有效的,可缩短手术时间,降低术后并发症发生率,值得进一步推广应用。Objective:To evaluate the clinical application value of indocyanine green fluorescence imaging in laparoscopic biliary re-exploration.Methods:Retrospective analysis was performed on the clinical data of 52 patients who underwent laparoscopic biliary re-exploration from Jan.2020 to Dec.2022.The clinical indexes related to 24 cases of fluorescence laparoscopy(fluorescence group)and 28 cases of ordinary laparoscopy(ordinary group)were compared.Results:There were no significant differences in baseline data,intraoperative combined biliary enteral drainage,postoperative biliary leakage,and calculi residual rates between the two groups(P>0.05).Operation time[(119.2±44.0)min vs.(159.0±52.4)min],extrahepatic bile duct search time[(21.0±7.8)min vs.(38.8±12.5)min],blood loss[(97.1±61.3)mL vs.(226.8±210.2)mL],the incidence of postoperative infection(8.3%vs.32.1%),the incidence of pancreatitis(4.2%vs.28.6%),postoperative drainage tube removal time[(2.7±1.1)d vs.(3.8±1.4)d],and postoperative hospitalization time[(6.4±2.3)d vs.(10.3±3.2)d]in fluorescence group and ordinary group were statistically significantly different(P<0.05).Conclusions:Indocyanine green fluorescence imaging is safe and effective in laparoscopic biliary re-exploration,which can shorten the operation time and reduce the incidence of postoperative complications.This technique is worthy of further application and promotion in clinical practice.

关 键 词：胆道探查术 腹腔镜检查 吲哚菁绿 荧光成像技术 

分 类 号：R657.4[医药卫生—外科学]